Diagnostic Challenges of Female Genital Tuberculosis
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2017, Vol 6, Issue 2
Abstract
Background: India accounts for one ffh of the global incidence of tuberculosis (TB) annually. Genital tract TB is one of the extra pulmonary presentations of TB leading to infertility among Indian women. Genital TB is a chronic disease and ofen asymptomatic with very few specifc complaints. Infertility is the most common clinical presentation of genital TB. Herein, we report a case of 32-year-old female patient suffering from abdominal pain and infertility for the last 8 months. Methods: Hysterosalpingography (HSG) and ultrasonography (USG) did not reveal characteristic radiological appearances of TB although USG detected the presence of a large fbroid in the right uterine wall. Histology, microscopy for acid fast bacilli, liquid culture and nucleic acid amplifcation assay targeting 64kDa protein encoding gene, the IS6110 element of endometrium biopsy were negative for tubercle bacilli. Results: Since the diagnosis of genital TB is elusive, antitubercular treatment (ATT) using isoniazid, pyrazinamide, rifampicin, and ethambutol was prescribed for two months followed by maintenance therapy with isoniazid and rifampicin for four months without any pregnancy outcome. Conclusion: However, the patient conceived spontaneously afer surgical removal of fbroid. Relating infertility to female genital tuberculosis due to high prevalence of TB in the country and ignoring the presence of uterine fbroid might not have been the right decision taken by the gynaecologist. Tis suggests the urgent need for an accurate method intended for diagnosis of female genital tuberculosis.
Authors and Affiliations
Chaudhary Vigi| Amity Institute of Biotechnology, Amity University, Jaipur, Rajasthan, India, Chaudhary Naveen| Smile and Dental Care, Nandpuri Main Market, Hawa Sadak, Jaipur, Rajasthan, India, Corresponding e-mail: nvnchaudhary@gmail.com
Keywords
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