Diagnostic Significance of Platelet – to – Lymphocyte Ratio in Evaluation of Sepsis

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Diagnostic Significance of Platelet – to – Lymphocyte Ratio in Evaluation of Sepsis

Journal Title: Journal of Indus Medical College - Year 2018, Vol 1, Issue 1

Abstract

Introduction: Sepsis is one the major cause of mortality and mortality in hospital settings. Many inflammatory markers have been proposed but their use is often limited due to unavailability and cost. Platelet – to – lymphocyte ratio (PLR) is now suggested as novel inflammatory marker in many conditions. Objective: To see the role of platelet – to – lymphocyte ratio (PLR) as an indicator of inflammation in patients with sepsis. Methodology: It was prospective cross sectional study performed on 415 patients. They were divided into patient/Group A (205), and healthy control/Group B (210). Patients above age of 18, admission time more than 24 hours and no co – morbid were included in the study. Demographic information was obtained from all patients. Blood sample was collected in EDTA tube and platelet count and lymphocyte were measured for PLR ratio. Data was analyzed using SPSS 21.0. P – value of <0.05 was considered as statistically significant. Results: Out of 415 patients, 143 (69.75%) were male and 62 (30.25%) were female in Group A; while in Group B, male and female were 136 (64.76%) and 74 (35.23%). Platelet – to – lymphocyte ratio (PLR) in group A was 117.24 ± 38.43 and in group B was 82.76 ± 41.88, with the p – value of <0.01. Conclusion: PLR was higher in septic patients as compared to control group. It is suggested as novel marker of inflammatory response to sepsis.

Authors and Affiliations

Shahzad Ali Jiskani, Ghulam Abbas Soomro, Dolat Singh

Keywords

EP ID EP690398
DOI -
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