Diagnostic Utility of Fine Needle Aspiration Cytology in Salivary Gland Tumors
Journal Title: Saudi Journal of Medical and Pharmaceutical Sciences - Year 2018, Vol 4, Issue 5
Abstract
Abstract:Fine needle aspiration cytology (FNAC) is a valuable adjuvant to preoperative assessment in patients with salivary tumors. The study aimed at studying the cytological features of benign and malignant salivary gland tumors, improving the diagnostic accuracy by using immunocytochemistry and correlating it with histopathology.A total of46 salivary gland tumors including twenty three cases each of benign and malignant tumors with available histology were included in the study.We studied 23 benign tumors, Pleomorphic Adenoma comprised 86.7% of all benign tumors and rest three cases were diagnosed as Warthin’s tumors. Positive correlation with histology was obtained in 95% in Pleomorphic adenoma and 100% in Warthin’s tumors. Twenty three malignant salivary gland tumors comprised 11 Mucoepidermoid carcinoma,10 Adenoid cystic and 2 Acinic Cell Carcinoma. Positive cytohistological correlation was established in eight out of eleven Mucoepidermoid carcinoma (Diagnostic Accuracy=72.7%) and all cases of Adenoid cystic and Acinic cell carcinoma. Diagnostic accuracy of FNAC for malignant tumors was 95.65%. Our study shows that FNAC is a highly sensitive and specific technique for diagnosis of salivary gland tumors. Immunocytochemistry can act as adjuvant in diagnosing salivary gland tumors, however it did not help in improving the diagnostic accuracy of FNAC in our study .Kappa value of 0.88 in our study indicated an excellent agreement between typing of salivary gland tumors on FNAC and histopathology. Keywords: Fine needle aspiration cytology, salivary gland tumors, immunocytochemistry.
Authors and Affiliations
Amit Goel¬, Manju Kaushal
Keywords
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