Diagnostic value of high sensitivity C-reactive protein levels in dedifferentiation of stable angina from unstable angina
Journal Title: Chronic Diseases Journal - Year 2014, Vol 2, Issue 2
Abstract
BACKGROUND: Differentiation of stable angina from unstable angina is important because they need different approaches. Few studies have been conducted to assess the diagnostic value of high sensitive C-reactive protein (hs-CRP) in differentiating these two diseases. This study aimed to evaluate the diagnostic value of hs-CRP levels for differentiating stable angina from unstable angina. METHODS: After signing the consent form, patients with unstable angina who referred to Tohid Hospital emergency in Sanandaj, Iran, and patients with stable angina who referred to the special clinic of the hospital were evaluated. Disease was confirmed by a cardiologist. Morning serum hs-CRP was tested using MONOBIND laboratory kit (USA). Data were analyzed by SPSS using Student’s independent t-test, Mann-Whitney U, chi-square, Fisher exact test, and receiver operating characteristic curve. RESULTS: hs-CRP levels in patients with stable angina and unstable angina were 1.6 (± 1.18) and 2.35 (± 1.30) mg/l, respectively (P = 0.025). The hs-CRP level ≥ 2.31 mg/l was the best cut-off point for differentiating stable from unstable angina. At this cut-off point, the sensitivity and specificity were 56% and 73%, respectively. Area under the curve was calculated to be 0.679 (95% confidence interval: 0.54-0.81) (P = 0.017). CONCLUSION: hs-CRP level is helpful for differentiating patients with stable angina from those with unstable angina. It is recommended to consider the hs-CRP level of 2.31 mg/l as the best cut-off point.
Authors and Affiliations
Reza Madadi, Katayoon Haddadian, Ebrahim Ghaderi
Keywords
Related Articles
- EP ID EP285004
- DOI -
- Views 150
- Downloads 0
The relationship between air pollution exposure and chronic obstructive pulmonary disease in Ahvaz, Iran
BACKGROUND: Air pollutants can have harmful effects on human health. Chronic obstructive pulmonary disease (COPD) is represented by a spectrum of obstructive airway diseases. The aim of this study was to evaluate the rel...
Analysis of the concept of family-based care in chronic diseases: Rodgers’s evolutionary approach
BACKGROUND: Considering the fact that hospitalization of a family member in the intensive care unit (ICU) can have a great impact on different aspects of the life of the patient’s family, the purpose of this study was to...
Investigating the structural relationship between math anxiety, Gray’s biological model of personality, and test anxiety through assessing the self-efficacy mediating role among junior girl students of Urmia City high schools, Iran
BACKGROUND: Test anxiety as a common educational phenomenon is closely related to the academic performance and achievement, and even the future performance of millions of students. Math anxiety is considered as one of th...
Student’s characteristics and fast food consumption
BACKGROUND: Many health hazards are known to be closely related to the consumption of fast food. The present study was conducted with the objective to investigate how students’ characteristics (attitude, control beliefs,...
The frequency of skin cancers in Kermanshah City, Iran, during the years 2003-2012
BACKGROUND: Skin cancer is the most common malignancy in the world, and besides the malignant type that has a high mortality rate, other cancers causes many complications and deaths as well. The incidence of skin cancer...