Diagnostic Value of The Ischemia Modified Albumin and Pentraxin 3 In Pediatric Appendicitis: A Meta Analysis
Journal Title: journal of clinical trials and experimental investigations - Year 2022, Vol 1, Issue 1
Abstract
Objective: In this meta-analysis, we aimed to review the diagnostic value of pentraxin 3 (PTX3) and ischemia-modified albumin (IMA) biomarkers in pediatric appendicitis. Method: Studies focusing on the value of PTX3 and IMA in the diagnosis of appendicitis were searched related to the PubMed database. Only randomized prospective clinical trials were included in this study. Results: After the screening, 6 articles based on the diagnostic value of IMA in appendicitis and 5 articles on the diagnostic value of PTX3 were reviewed. A total of 5 studies were included. The data of the 385 patients were reviewed. Sensitivity of PTX3 was 73-92% and specificity 88-100%, while IMA sensitivity was 89-96.7% and specificity was 26-99.7% in acute appendicitis. Conclusion: Although the results of the present study indicate that PTX3 and IMA can be shown as biomarkers in the differential diagnosis of acute abdomen, further study is needed to determine the cut-off value.
Authors and Affiliations
Diego Falchi, Ayten Ceren Bakır, Toni Risteski, Hani Abu Tziam, Seçil Yüksel, Sena Inal Azizoğlu
Keywords
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- EP ID EP708530
- DOI https://doi.org/10.5281/zenodo.6857498
- Views 73
- Downloads 1
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