Dietary or Supplementary Intake Modulates Inflammatory Response in Asthma
Journal Title: Global Journal of Allergy - Year 2015, Vol 1, Issue 2
Abstract
The importance of diet and supplement intake in the onset and development of asthma has been advocated recently, and it may be important in the prevention and management of bronchial asthma. Long-chain n-3 polyunsaturated fatty acids (LCn3PUFAs), vitamins (Vit), choline, and probiotics may be candidates to reduce medication use and provide some protection from risk. Experimental studies of diet in bronchial asthma have demonstrated modification of pulmonary function and the immune system through mechanisms involving antioxidant effect, T-helper (Th) 2 and Th17 inhibition, tolerogenic regulatory T cell (Treg) function promotion, nuclear transcription factors and epigenetic regulation. Although studies in animal models have provided evidence of supportive effects of diet in asthma, there have been few longitudinal studies of dietary or supplement intake and asthma, and the available epidemiological data remain controversial and inconclusive.
Authors and Affiliations
Matsumura Yasuhiro
Keywords
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- DOI 10.17352/2455-8141.000006
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