Different Pharmaceutical Products Need Similar Terminology
Journal Title: The AAPS Journal - Year 2014, Vol 16, Issue 1
Abstract
The online version of this article (doi:10.1208/s12248-013-9532-0) contains supplementary material, which is available to authorized users.
Authors and Affiliations
Daan J. A. Crommelin, Jon S. B. de Vlieger, Vera Weinstein, Stefan Mühlebach, Vinod P. Shah, Huub Schellekens
The cytoplasmic escape and nuclear accumulation of endocytosed and microinjected HPMA copolymers and a basic kinetic study in hep G2 cells
The development of macromolecules as drugs and drug carriers requires knowledge of their fate in cells. To this end, we studied the internalization and subcellular fate of N-(2-hydroxypropyl)methacrylamide (HPMA) copolym...
Mechanistic Pharmacokinetic/Target Engagement/Pharmacodynamic (PK/TE/PD) Modeling in Deciphering Interplay Between a Monoclonal Antibody and Its Soluble Target in Cynomolgus Monkeys
The online version of this article (doi:10.1208/s12248-013-9545-8) contains supplementary material, which is available to authorized users.
International Guidelines for Bioequivalence of Locally Acting Orally Inhaled Drug Products: Similarities and Differences
The online version of this article (doi:10.1208/s12248-015-9733-9) contains supplementary material, which is available to authorized users.
Supersaturated Self-Nanoemulsifying Drug Delivery Systems (Super-SNEDDS) Enhance the Bioavailability of the Poorly Water-Soluble Drug Simvastatin in Dogs
This study investigates the potential of supersaturated self-nanoemulsifying drug delivery systems (super-SNEDDS) to improve the bioavailability of poorly water-soluble drugs compared to conventional SNEDDS. Conventional...
Oral bioavailability in pigs of a miconazole/Hydroxypropyl-γ-cyclodextrin/ L-tataric acid inclusion complex produced by supercritical carbon dioxide processing
The objective of this study was to determine the pharmacokinetic parameters of miconazole after oral administration of a miconazole/hydroxypropyl-γ-cyclodextrin(HPγCD)/ L-tartaric acid inclusion complex p...