Differential Diagnosis of Alzheimer’s Disease and Other Types of Dementia with Development of Neuroimaging Techniques (PET, SPECT, and MRI)
Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 7
Abstract
Number of neurodegenerative diseases that cause dementia, such as Alzheimer’s disease, dementia with Lewy bodies, and front temporal dementia. In medical diagnosis many people’s cannot differentiate between Dementia and Alzheimer’s disease, neuroimaging has played a variety of roles in the study of Dementia and Alzheimer disease (AD) over the past four decades. Initially, computed tomography (CT) and then magnetic resonance imaging (MRI) were used diagnostically to rule out other causes of dementia. recent study have shown the value of neuroimaging techniques including Structural MRI( Magnetic resonance imaging) and functional imaging by SPECT(Single Photon Emission Computerized Tomography) as well as 18FFDG PET (Positron Emission Tomography) which are widely used in the diagnosis of Alzheimer’s disease to delineate the differential diagnosis with other types of Dementia . These modalities and their particular utilities are discussed in this review The aim of the study is to evaluate functional differences that might reflect differences in the distribution of their respective pathologies. These evaluation is very important because extensive neuropath logical damage occurs before clinical diagnosis, so preclinical discrimination between people who will and will not ultimately develop AD is critical for treatment of the disease in its earliest stages.
Authors and Affiliations
Mwahib Sid Ahmed
Keywords
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