Diffuse Nodular Lymphoid Hyperplasia of Colon in a Child- A Case Report with Review of Literature

Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 12

Abstract

Diffuse Nodular Lymphoid Hyperplasia (DNLH) of the Gastrointestinal Tract (GIT) is an uncommon, benign reactive lesion occurring in all age groups. It is seen distributed throughout the GIT. DNLH is characterized by diffuse mucosal polypoid masses of 2-5 mm diameter. Commonly mistaken for various polyposis syndromes on endoscopy, It may present with abdominal pain, recurrent hematochezia, intussusception, intestinal obstruction and anaemia. Childhood DNLH is associated with various etiologies from food hypersensitivity to immunodeficiency syndromes. As DNLH is mostly a benign, reactive process, histopathology plays an important role in its recognition to prevent misdiagnosis and radical procedures. Here, we present a rare case of DNLH of colon in a two year old female child, presenting with abdominal distension. Colonoscopy revealed multiple colonic polyps. Total colectomy specimen revealed multiple, sessile polyps of 0.2 to 0.3cm carpeting the entire colonic mucosa. Microscopy revealed polyps comprised of lymphoid follicles with germinal centre in the mucosal and submucosal location.

Authors and Affiliations

Chikkanaganna Pillavenkataswamy Manjula, Belur Venugopal Suguna, sr Niveditha, Sreedhar Murthy

Keywords

Related Articles

Alterations in the Reactive Oxygen Species in Peripheral Blood of Chronic Myeloid Leukaemia Patients from Northern India

Introduction: There is a significant difference in the Reactive Oxygen Species (ROS) levels of Chronic Myeloid Leukaemia (CML) patients before and during treatment with Tyrosine Kinase Inhibitors (TKIs). This is because...

Use of Oral Antiseptics and its Association with Cardiovascular Events: Review

ABSTRACT Most nitrates which circulate in the plasma become concentrated in salivary glands and release into saliva. Nitrate molecules are reduced to nitrites via oral facultative anaerobic bacteria. After swallowing, so...

Morphometry of Proximal Femur in Indian Population

Introduction: Total hip arthroplasty is a commonly performed surgery now-a-day. There are regional and racial variations in the stature of the population worldwide. So there is always need of population specific data for...

Versatility of Tongue Flaps for Closure of Palatal Defects- Case Report

Palatal defects following congenital anomalies, traumatic injuries, benign and malignant pathologies frequently require resection and reconstruction. Reconstruction of these defects is challenging and complex due to the...

Characterisation of Multidrug-resistant Alcaligenes faecalis Strain AF1 Isolated from Patient of RUTIs: A Study from Bangladesh

ABSTRACT Introduction: Alcaligenes faecalis is a common environmental bacterium that often infects human as an opportunistic pathogen. It rarely causes Urinary Tract Infection (UTI) in human; however, infection brings s...

Download PDF file
  • EP ID EP367435
  • DOI 10.7860/JCDR/2017/32163.10939
  • Views 82
  • Downloads 0

How To Cite

Chikkanaganna Pillavenkataswamy Manjula, Belur Venugopal Suguna, sr Niveditha, Sreedhar Murthy (2017). Diffuse Nodular Lymphoid Hyperplasia of Colon in a Child- A Case Report with Review of Literature. Journal of Clinical and Diagnostic Research, 11(12), 3-5. https://europub.co.uk/articles/-A-367435