Diffuse Nodular Lymphoid Hyperplasia of Colon in a Child- A Case Report with Review of Literature

Journal Title: Journal of Clinical and Diagnostic Research - Year 2017, Vol 11, Issue 12

Abstract

Diffuse Nodular Lymphoid Hyperplasia (DNLH) of the Gastrointestinal Tract (GIT) is an uncommon, benign reactive lesion occurring in all age groups. It is seen distributed throughout the GIT. DNLH is characterized by diffuse mucosal polypoid masses of 2-5 mm diameter. Commonly mistaken for various polyposis syndromes on endoscopy, It may present with abdominal pain, recurrent hematochezia, intussusception, intestinal obstruction and anaemia. Childhood DNLH is associated with various etiologies from food hypersensitivity to immunodeficiency syndromes. As DNLH is mostly a benign, reactive process, histopathology plays an important role in its recognition to prevent misdiagnosis and radical procedures. Here, we present a rare case of DNLH of colon in a two year old female child, presenting with abdominal distension. Colonoscopy revealed multiple colonic polyps. Total colectomy specimen revealed multiple, sessile polyps of 0.2 to 0.3cm carpeting the entire colonic mucosa. Microscopy revealed polyps comprised of lymphoid follicles with germinal centre in the mucosal and submucosal location.

Authors and Affiliations

Chikkanaganna Pillavenkataswamy Manjula, Belur Venugopal Suguna, sr Niveditha, Sreedhar Murthy

Keywords

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  • EP ID EP367435
  • DOI 10.7860/JCDR/2017/32163.10939
  • Views 54
  • Downloads 0

How To Cite

Chikkanaganna Pillavenkataswamy Manjula, Belur Venugopal Suguna, sr Niveditha, Sreedhar Murthy (2017). Diffuse Nodular Lymphoid Hyperplasia of Colon in a Child- A Case Report with Review of Literature. Journal of Clinical and Diagnostic Research, 11(12), 3-5. https://europub.co.uk/articles/-A-367435