Diffusion and Chemical Shift Magnetic Resonance Imaging Properties of Lumbar Bone Marrow; Correlation with Osteoporosis
Journal Title: Türk Osteoporoz Dergisi - Year 2018, Vol 24, Issue 3
Abstract
Objective: To investigate whether or not diffusion-weighted imaging (DWI) of vertebral bone marrow or dual-echo chemical shift imaging (CSI) achieved by magnetic resonance imaging (MRI) can be used in the diagnosis of osteoporosis. Materials and Methods: Twenty-nine postmenopausal women patients (mean age 53.9±9 years) who underwent upper abdominal MRI and dual-energy X-ray absorptiometry (DXA) were included in the study retrospectively. A total of 87 lumbar vertebras which appropriate were divided into subgroups as normal, osteopenic and osteoporotic according to T-scores. Apparent diffusion coefficient (ADC) values were calculated from DWI and signal intensities (SI) that measured in T1 dual-echo sequences were compared between groups. The fat fractions of the vertebral body were measured based on the signal intensity index and vertebral spleen ratio (VSR) formulas previously used for adrenal adenomas. Results: The mean vertebral ADC values were 0.61±0.1 x 10-3 mm2/s in the normal group, 0.59±0.1 x 10-3 mm2/s in the osteopenic group, and 0.56±0.1 x 10-3 mm2/s in the osteoporotic group and there was no significant difference between them. The SI in out-of-phase sequence, SI index, and VSR were able to discriminate the osteoporotic group that had sustained fracture risks from the healthy and osteopenic ones. The sensitivities of the out-of-phase SI, SI index and VSR were 65.2%, 61.1% and 71%, respectively, while their specificities were 61.1%, 63.8%, and 61.1%, respectively. Conclusion: The diffusion properties of bone marrow are not fully affected by osteoporosis. The DXA scores appear to be moderately related to the chemical composition of bone marrow rather than its cellularity. CSI based fat quantification can be a referrer in the decision to initiate treatment by giving an idea of the presence of osteoporosis
Authors and Affiliations
Betül Kızıldağ, Mehmet Akif Sarıca, Nursel Yurttutan
Keywords
Related Articles
- EP ID EP552078
- DOI 10.4274/tod.galenos.2018.95530
- Views 92
- Downloads 0
Dual Etiologic Back Pain in Pregnancy: A Case Report with Lumbar Disc Herniation and Transient Osteoporosis of the Bilateral Hip
Low back pain in pregnancy is a common complaint. It has been reported that the pregnancy is an independent risk factor for lomber disc herniation and may worsen the existing herniation. Transient osteoporosis of the hip...
Complex Regional Pain Syndrome After Herpes Zoster: A Case Report
A 78-year-old male patient, diagnosed with herpes zoster infection, had color change, stiffness, swelling and burning pain on his left hand. Hand joints were painful, joint range of motion decreased and hyperpigmented, m...
Polymorphisms within RANKL and Osteoprotegerin Genes in Low Bone Mass among Postmenopausal Indonesian Women
Objective: Prior studies have shown that receptor activator of nuclear factor-B ligand (RANKL) and osteoprotegerin (OPG) have an essential role in bone remodeling and osteoporosis. This study aimed to investigate the ass...
Postpartum Unilateral Sacral Stress Fracture Mimicking Lumbar Radiculopathy: Case Report
Postpartum sacral stress fracture is a very rare clinical entity. Because of the ambiguous clinical and radiological findings, it is often diagnosed late. A case of a postpartal 25-year-old female patient presented with...
The Seasonal and Meteorological Relationships of Diagnostic Distribution of Patients Presenting with Musculoskeletal Complaints According to Gender
Objective: The seasonal relationship of incidence of musculoskeletal system (MSS) pathologies according to gender and their meteorological variability has not been investigated satisfactorily. The aim of this study is to...