Diffusion weighted (DW) MRI in assessment of renal function - a preliminary study to determine the Apparent Diffusion Coefficient (ADC) values of kidneys with normal function
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 12
Abstract
Aim: To determine the ADC values of kidneys in patients with normal serum creatinine values as an initial step to investigate the clinical potential of diffusion-weighted imaging (DWI) in assessing renal function in comparison with serum markers of renal function. Materials and Methods: MR imaging is performed on 1.5 Tesla MR machine (Siemens) Diffusion weighted images are obtained at b values 0, 50. 400 and 800. Using automated ROI delineation methods ADC values are measured in the upper pole, interpolar region and lower pole of both kidneys. The mean ADC values were recorded for each kidney for each patient is recorded. The patients selected for this study had normal values for serum markers of renal function. Results: The ADC value for renal parenchyma varied from 1.697x 10-3 mm 2 /s to 1.948x10-3 mm 2 /s with a mean ADC value of kidneys ranging from 1.730x10-3 mm 2 /s to 1.885x10-3 mm 2 /s Conclusion: Diffusion weighted MR imaging of the kidney can be useful imaging modality in the early determination of renal parenchymal disease especially with unilateral dysfunction. ADC values may predict abnormality earlier than serum markers of renal function.
Authors and Affiliations
Dr Bindu R Kumar
Keywords
Related Articles
- EP ID EP521097
- DOI -
- Views 39
- Downloads 0
Preterm Prelabour Rupture of Membranes at 34-37 Weeks’ Gestation: Intentional Delivery versus Expectant Management
Objectives: In this prospective study we wanted to prove that intentional delivery as compared to expectant management for PPROM at 34 – 37 weeks’ gestation will be associated with improved maternal and perinatal outcome...
Efficacy of Ichthammol Glycerin Pack and Steroid Antibiotic Pack as Initial Treatment of Acute Otitis Externa: A Comparative Study
Introduction: Otitis externa, characterized by general oedema and erythema of the external auditory canal, can be treated by various modalities including aural toilet, topical antibiotic agents, with or without corticost...
Clonidine as an Adjuvant to 0.5% Ropivacaine for Supraclavicular Brachial Plexus Block in Patients Undergoing Orthopedic Surgery of Forearm and Hand - A Randomized Controlled Trial
Background: Regional anesthesia blocks are being increasingly used to cater to the variety of surgical procedures for the forearm and hand. Methods to enhance the duration of analgesia and shorten the onset and lengthen...
A Study of Pattern of Medico-Legal Cases in a Premier Hospital in Delhi
Employee State Insurance Hospital (ESIH) is catering to the worker population and their dependants and so occupation related medico-legal cases are expected to occur more in such a hospital. This study was done to analyz...
Study of Antioxidant enzymes- Superoxide dismutase, Catalase and Glutathione Peroxidase level in Breast cancer
There are several natural occurring antioxidants in our body which serve to counteract against free radicals generated in our body as byproducts of various metabolic reactions. Any deficiency of these antioxidant in body...