DIOSPYROS MELANOXYLON ROXB IN CANCER PREVENTION: PHARMACOLOGICAL SCREENING, PHARMACOKINETICS AND CLINICAL STUDIES
Journal Title: International Journal of Pharmacognosy - Year 2017, Vol 4, Issue 7
Abstract
Plants contain a galaxy of phytoconstituents which accounts for their remedial worth. This plant has been used expansively for its medicinal value all over the world. Different plant parts have been used for its different pharmacological screening, including cancer therapy and leaves can be wrapped to create the “beedi” filled with tobacco which has outsold conventional cigarettes in India. Extraction of plant material with organic solvent and elucidation of pure compounds using different technique with different solvent system are extremely imperative limitation. Elucidation of pentacyclic triterpenoid, ursolic acid from D. melanoxylon and molecular mechanisms has vast chances for the development of enhanced therapy for different diseases, including cancer, and clinical studies. Our extensive intention of this study is to give a general delineate on the thyme D. melanoxylon and its cancer prevention potential, diverse pharmacological action, ethnomedicinal uses and chemical compounds. We also focus the extraction methodology, elucidation, pharmacokinetic and various clinical trials of ursolic acid chiefly obtained from D. melanoxylon.
Authors and Affiliations
Md. Harun Al Rashid et al.
Keywords
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- EP ID EP428709
- DOI 10.13040/IJPSR.0975-8232.IJP.4(7).217-23
- Views 107
- Downloads 0
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