DISSEMINATED INFECTIONS AS CAUSE OF DEATH DETECTED AT ORGAN AUTOPSY- 2- YEAR STUDY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 11
Abstract
BACKGROUND Tuberculosis and Malaria are among the leading causes of infectious disease-related deaths worldwide. Plasmodium falciparum is almost always responsible for the most severe cases of malaria, leading to multi organ failure and higher mortality rates among the plasmodium species. India has the highest burden of TB in the world, an estimated 2 million cases annually, and accounting for approximately one fifth of the global incidence. Despite the availability of effective treatment for most cases, tuberculosis is still a cause of death in our environment; as in some cases, the diagnosis of tuberculosis may not be established until after the patient had died and an autopsy has been performed. MATERIALS AND METHODS The present prospective study includes 93 cases of medico legal organ-autopsies reported at Osmania General Hospital/Osmania Medical College during a period of 2 years. Of these, cause of death in 3 cases was attributed to disseminated tuberculosis involving multiple organs and one rare case of disseminated Plasmodium falciparum malaria was reported involving multiple organs such as heart, brain, liver, kidneys and spleen in a 26-year-old male who presented with a brief history of fever and vomiting. RESULTS The presence of unspecific symptomatology, insufficient cost-effectiveness of the diagnostic tests and precocious death, are identified as the most frequent causes of undiagnosed cases of deaths due to infectious aetiology. CONCLUSION Infectious diseases are under-recognized cause of sudden death, usually autopsy can help in identifying the cause of death in such cases.
Authors and Affiliations
Ezhil Arasi N, Shakira Anjum, Shrinivas Bheemrao Somalwar, Abdul Aleem
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