Diverse Genetic Screening and Counseling throughout the Iranian Population
Journal Title: Annual Research & Review in Biology - Year 2017, Vol 18, Issue 6
Abstract
Background and Aim: The recent decades have witnessed increasing possibilities for genetic testing and screening. In the Iran, since the 1970s, individuals and their family members could obtain genetic counselling for their own risk or diagnosis of a serious genetic disorder or that of their offspring. The aim of this study was to determine the results of screening for genetic disorders in Najafabad-Isfahan. Methodology: This study was conducted on 2,500 families of Najafabad-Isfahan. 250 of these families were randomly referred for genetic counseling. In these families, the degree and type of disability, the death of children under 2 years of age, abortion and stillbirth were investigated and genetic counseling and tests were carried out in some families. Results: The findings of this study showed family marriage have been 41% in students' parents and 31% in couples. The highest type of disability in order to frequency was consist of intellectual disability, musculoskeletal, congenital disorders, deafness, microspheres, abortion and stillness, heart problems, vision, blood diseases, CP, death of children under 2 years of age, hydrocephalus, metabolic and autism. Conclusion: Based on the results of present study it was shown that most disabilities happened in families with familial marriage or families with a history of disability and genetic counseling can be done by informing people at risk to lose the chance of having a child with a disability.
Authors and Affiliations
Zakieh Arab, Asghar Arshi, Mohammad-Javad Arshi, Zahra Yousefzadeh, Fatemeh Salmani
Keywords
Related Articles
- EP ID EP313534
- DOI 10.9734/ARRB/2017/36990
- Views 60
- Downloads 0
Assessment of Physico-chemical Characteristics and Functionality of Existing Potable Water Sources in Disaster Prone Area of South-West Coastal Region in Bangladesh
The people of Bangladesh are dependent mostly on groundwater for their drinking purpose. But due to salinity and arsenic problem in ground water, alternative techniques such as pond sand filters (PSF), rainwater harvesti...
Multi-locational Screening of Genotypes of Cowpea [Vigna unguiculata (L) Walp] for Resistance to Viral Infection
Viral diseases are an important biotic constraint to cowpea production in sub-Saharan Africa. The use of resistant varieties is the most effective approach in managing viral diseases. In order to identify sources of resi...
Effect of Ethanolic Extract of Propolis on Humoral Immunity in Laboratory Animals
Background: Propolis is a material that collected by bees from different plants and unites with beeswax and enzymes of salivary glands of fly. Aim: The study was designed to assess humoral immunity activity of propolis...
Analysis of Tissue Alterations and Quantitative Histopathological Indices in Rhamdia quelen (Quoy & Gaimard, 1824) and Metynnis maculatus (Kner, 1858) During Treatment of Ichthyophthiriasis
Aims: The present study aimed to describe the histological alterations observed in gills of Rhamdia quelen and Metynnis maculatus during treatment of white spot disease and to compare three quantitative indices of gill a...
Biochemical Assessment of Picralima nitida Seeds on Oxidative Stress Parameters of Albino Rats
The effects of different percentage concentrations (5%, 10%, 20% and 30%) of ground seeds of Picralima nitida on the concentrations of ascorbic acid (AA), glutathione (GSH) and the activities of superoxide dismutase (SOD...