DNA CLEVAGE STUDIES OF THE ETHANOLIC EXTRACTS OF THE BARK OF BAUHINIA TOMENTOSA L. AND THE WHOLE PLANT OF MUSSAENDA FRONDOSA L.
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2011, Vol 2, Issue 9
Abstract
DNA cleavage studies of the ethanolic extracts of the bark of Bauhinia tomentosa L. (Fam, Fabaceae) and the whole plant of Mussaenda frondosa L. (Fam, Rubiaceae) have been performed. The cleavage of pUC18 DNA was evaluated by agarose gel electrophoresis. Both the plant extracts show a dose dependent increase from lower concentration to higher concentration. Ethanol extract of Bauhinia tomentosa L showed more cleavage activity than that of the Mussaenda frondosa L. The results have been compared with the standard DNA cleavage agent FeSO4.
Authors and Affiliations
Gopalakrishnan S. , Vadivel E.
Keywords
Related Articles
- EP ID EP145504
- DOI -
- Views 108
- Downloads 0
DEMOGRAPHIC DISTRIBUTION OF THE DISEASE GRAHANI (MAL ABSORPTION SYNDROME) AND ITS EVALUATION BASED UPON ETIO-PATHOLOGICAL SIGNIFICANCE
Ayurveda has its own philosophy and its unique approach. It has given good definition for health and disease “Vikaro dosha vaishamyam, dosha samyam arogata” i.e., Tridosha if get vitiated alone or together results in di...
ISOLATION, PURIFICATION AND CHARACTERIZATION OF ACTIVE COMPOUND FROM ANDROGRAPHIS PANICULATA L AND PHYLLANTHUS AMARUS L AND TESTING THE ANTI-VENOM ACTIVITY OF THE DI-HERBAL EXTRACT BY IN-VITRO AND IN-VIVO STUDIES
The mortality associated with snake bites is a serious medical, social and economic problem in many countries and about 35,000 to 50,000 people reportedly die of snakebites in India; hence in this study an attempt has be...
ASSESSMENT OF LIFESTYLE-RELATED RISK FACTORS CONTRIBUTING FOR CHRONIC NON COMMUNICABLE DISEASE IN PATIENTS VISITING RURAL TERTIARY CARE HOSPITAL
Chronic Non-communicable diseases remain an area of high public health concern especially in developing countries where growing middle class and ever changing lifestyle have led to the rapid increase in the burden of non...
CURCUMIN: A YELLOW MAGICAL SPICE OF KITCHEN FOR TREATMENT OF RHEUMATOID ARTHRITIS
Over many millennia, natural products were the only means to treat diseases and injuries. With the advances in molecular biology and combinatorial chemistry during the past few decades, natural products have taken a seco...
PRESCRIBING PATTERN AND USE OF STEROIDS IN ASTHMA PATIENTS
Asthma affects people of all ages, India has an expected 15-20 million asthmatics according to world health organisation. Steroids are widely prescribed in asthmatic patients, forming a part of standard and most treatmen...