Do we Need New Therapies for Diabetes?
Journal Title: Diabetes Research – Open Journal - Year 2015, Vol 1, Issue 3
Abstract
Diabetes research and practice cluster (drug developers, payers, regulators and physicians) often (and especially in recent times) question the need of new therapies. Why would we need new therapies nowadays, when we have 9 classes (insulins, sulfonylureas, biguanides, meglitdes, thiazolidnediones, alpha-glucosidase inhibitors, DPP-4 inhibitors, SGLT2 inhibitors and GLP-1 receptor agonists),1 rapidly increasing number of biosimilars2 and uncountable number of generics? Reasonable question. Does it make sense to invest billions of dollars in messy global cardiovascular outcomes trials (as requested by diabetes drug development guidelines3 ) or to play love attraction games with payers4 so they “fall in love” with the “new” pill (most often combo with the good old metformin)?
Authors and Affiliations
Dimiter Dimitrov
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