Does Acute Kidney Injury Alter Energy Metabolism of Septic Patients?
Journal Title: Archives of Renal Diseases and Management - Year 2016, Vol 2, Issue 1
Abstract
Background: The determination of resting energy expenditure (REE) in critically ill patients is essential to prevent hypo and hyper alimentation. Objectives: This study aims to describe the REE in septic patients with and without acute kidney injury (AKI) and compare by examining the REE estimated by Harris-Benedict equation (HB) with the REE measured by indirect calorimetry (IC). Methods: Prospective study was performed in septic patients older than 18 years, undergoing mechanical ventilation, with or without AKI defined by KDIGO criteria, and admitted to the Intensive Care Unit of University Hospital. The REE was estimated by HB equation and measured by IC within 72 hours after the diagnosis of sepsis and seven days after the initial measure. Results: Sixty-eight patients were evaluated, age was 62.49±16.6 years, 63.2% had AKI, and SOFA was 9.81±2.35. The measured REE was 1857.53±685.32 kcal, while the estimated REE was 1514.87±356.72 kcal, with adequacy of 123.49±43%. Septic patients without AKI (n=25) and with AKI (n=43) had measured REE statistically higher than the estimated one (1855 kcal (1631.75-2052.75) vs. 1551 kcal (1349 -1719.25), p=0.007 and 1868.0 kcal (1219.5-2364.75) vs. 1388 kcal (1254-1665.5), p=0.026, respectively). There was no significant difference between the two groups in measured and estimated REE and in evolutional REE. Conclusion: The REE measured by IC was significantly higher than that estimated by HB in both septic patients with and without AKI. There was no significant difference between the septic patients with and without AKI in REE, suggesting that AKI does not influence the REE of septic patients.
Authors and Affiliations
Soncini Sanches Ana Cláudia, de Góes Cassiana Regina, Bufarah Nogueira Berbel, Balbi André Luis, Ponce Daniela
Keywords
Related Articles
- EP ID EP343417
- DOI 10.17352/2455-5495.000011
- Views 93
- Downloads 0
The Lack of the Knowledge about the Postprandial Blood Glucose by the Education using the Single Absolute Tool for the Diabetic Dietary Therapy in Japan
The diabetic dietary therapy is the primary strategy to control and prevent the progression of diabetes and its complications. Energy counting based on diabetic food exchange lists, in which 1 exchange unit is equivalent...
Use of Interpreters for non-native English speaking Kidney Allograft Recipients and outcomes after Kidney Transplantation
Background: Language barriers are associated with worse health outcomes in the general population but data in kidney transplantation is lacking. This study tested the hypothesis that non-native English speakers using int...
Nephrolithiasis in hypercalcemic and normocalcemic primary Hyperparathyroidism
Primary hyperparathyroidism (PHPT) is a common condition affecting up to 4 per 1000 of population, and the majority of cases are due to adenoma or hyperplasia of the gland [1]. This endocrine disorder may either develop...
Nephrolithiasis Associated with Normocalcemic or Hypercalcemic Primary Hyperparathyroidism: An Update on Medical Management
Primary hyperparathyroidism (PHPT) is a disease involving a broad range of alterations of calcium homeostasis, sustained by parathyroid hormone (PTH) levels that are clearly abnormal. The anomalies directly associated wi...
Effectiveness and Tolerability of Febuxostat vs Allopurinol in patients with Chronic Kidney Disease (CKD) on Conservative Therapy
Uric Acid appears to be one of the most important prognostic markers and one of the principal risk factors for cardiovascular diseases. The aim of our study was to assess three groups of patients: a first group treated w...