Does chronic kidney disease impact on cardiovascular complications and mortality in the elderly?
Journal Title: Postępy Nauk Medycznych - Year 2013, Vol 26, Issue 2
Abstract
Chronic kidney disease (CKD) is highly prevalent among elderly patients and the risk of CKD increases with age. Reduced glomerular filtration rate (GFR) is well-recognized risk factor for development of atherosclerotic cardiovascular (CVS) disease. It is also an independent predictor of increased all-cause and CVS death. Albuminuria, another parameter of kidney damage, is even better prognostic factor for adverse outcome. Excessive risk of CVS complications in patients with CKD translates into relatively lower risk of end-stage renal disease in elderly people as compared to the younger age groups – much more patients in an advanced age with CKD die before reaching the more advanced stages of CKD and need of dialysis or kidney transplantation. Although many therapeutic strategies applied to limit the burden of CVS disease and mortality in the general population were not tested in CKD, it seems appropriate to assume than many of them are also effective in patients with CKD. These include: aspirin, statins, angiotensin-converting enzyme inhibitors, beta- blocking agents and revascularization procedures. Elderly patients with CKD deserve special attention and care to limit their excessive CVS mortality.
Authors and Affiliations
Tomasz Stompór, Katarzyna Pankrac
Keywords
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