Does height catch-up in schoolchildren have an effect on bone mass in adolescents? Analysis in a Brazilian birth cohort

Journal Title: Jornal de Pediatria - Year 2019, Vol 95, Issue 5

Abstract

Objective To analyze the effect of height catch-up at school age on the bone mass of adolescents of a Brazilian birth cohort. Methods A cohort study using data obtained from the three moments (birth, 7/9 years and 18/19 years of age) of the Cohorts-RPS study. Height catch-up was defined based on the difference between the schoolchild's z-score and birth z-score. The adolescents’ bone mineral mass was analyzed using the z-score index for the lumbar spine measured by dual emission X-ray absorptiometry. A theoretical model was developed for the proposed analysis using directed acyclic graphs paired through the nearest-neighbor matching propensity score using the STATA software, version 14.0. The level of significance was set at 5%. Results Of the 297 studied children, 24.5% achieved height catch-up. The bone mass below the expected for age was observed in 5.39% of the subjects. The mean lumbar spine z-score was −0.34 (±1.01). After the adjustment, no effect was observed between height catch-up at school age and bone mass in adolescents (Coeff=0.598; 95% CI −0.117 to 1.313; p=0.101). Conclusion Even using the directed acyclic graphs and the causal inference method by adjusting the propensity score, the height catch-up did not seem to affect bone mass in adolescents, a result perhaps related to the sample size.

Authors and Affiliations

Livia Rodrigues

Keywords

Related Articles

Atypical manifestations of Epstein–Barr virus in children: a diagnostic challenge

Objective Clarify the frequency and the pathophysiological mechanisms of the rare manifestations of Epstein–Barr virus infection. Sources Original research studies published in English between 1985 and 2015 were selecte...

Febrile seizures: a population-based study

Objectives To determine the prevalence of benign febrile seizures of childhood and describe the clinical and epidemiological profile of this population. Methods This was a population-based, cross-sectional study, carrie...

The impact of asthma and its treatment on growth: an evidence-based review

Objectives To assess the impact of asthma and its treatment (inhaled corticosteroids and other control medications) on growth. Data sources The authors searched PubMed (up to August 24, 2018) and screened the reference...

Microcephaly and Zika virus: a clinical and epidemiological analysis of the current outbreak in Brazil

Objective This study aimed to critically review the literature available regarding the Zika virus outbreak in Brazil and its possible association with microcephaly cases. Sources Experts from Instituto do Cérebro do Rio...

Postnatal management of growth failure in children born small for gestational age

Objectives To discuss the etiology and growth consequences of small size at birth and the indications, effects, and safety of biosynthetic growth hormone therapy in children born small for gestational age. Source of dat...

Download PDF file
  • EP ID EP646116
  • DOI 10.1016/j.jped.2018.05.015
  • Views 71
  • Downloads 0

How To Cite

Livia Rodrigues (2019). Does height catch-up in schoolchildren have an effect on bone mass in adolescents? Analysis in a Brazilian birth cohort. Jornal de Pediatria, 95(5), 607-613. https://europub.co.uk/articles/-A-646116