Does midazolam affect postoperative nausea and vomiting?
Journal Title: Ege Tıp Dergisi - Year 2014, Vol 53, Issue 4
Abstract
Aim: Postoperative nausea and vomiting (PONV) is one of the complications in a prolonged length of stay in postoperative care unit and hospital and thus, affects postoperative morbidity. We aimed to compare the effects of intraoperative midazolam and ondansetron on PONV. Materials and Methods: Upon obtaining ethical committee consent, 60 patients (ASA I-II) agreed to participate in the randomized, prospective and double-blinded study for elective thyroid and parathyroid surgery were enrolled. Following removal of thyroid / parathyroid tissue the patients in Group M were administered midazolam IV 2 mg, and the patients in Group O were administered ondansetron IV 4 mg. Thirty minutes before the end of surgery the patients were given paracetamol. The duration of anesthesia and surgery, wake-up time, time until Aldrete score reached 10, nausea and vomiting frequency, OAS/S and VAS scores additional antiemetic need were recorded for 24 hours. Results: There were no differences between the two groups with respect to demographic parameters. However, the operation time for Group O was longer. The total amount of fentanyl used, wake-up time, and the need for additional antiemetics in the two groups were not significantly different. The time until Aldrete score reached was significantly longer in Group M than in Group O. (p<0.05). The vomiting frequency was higher in Group M than in Group O at the 24th hour (p=0.005). Conclusion: In this study where the effects of midazolam and ondansetron on PONV were compared, it was determined that sedation achieved with midalozam may be effective in the early postoperative period.
Authors and Affiliations
A Öztaş, E Erkılıç, T Gümüş, O Kanbak
Keywords
Related Articles
- EP ID EP348892
- DOI 10.19161/etd.344087
- Views 101
- Downloads 0
Comparison of the results of ultrasonography-guided percutaneous liver mass biopsy performed with 18 and 20 gauge needles
Aim: To evaluate the role of using 18 Gauge (G) and 20G sharp needles in ultrasonography (US)-guided percutaneous liver mass biopsy regarding diagnostic success and efficacy is aimed. Materials and Methods: Sixty patient...
Pulmonary resection for the patients with larynx and pulmonary malignancies
Aim: Larynx and pulmonary malignancies can be seen synchronously or metachronously as a result of common etiological factors. In this study, we aimed to present our clinical approach and management methods of these patie...
Herediter multiple ekzostoz
Herediter multiple ekzostoz, çoğunlukla uzun kemiklerin juksta-epifizer bölgesinden köken alan ekzositozlarla karakterize otozomal dominant bir hastalıktır. Hastalar en sık eklem yakınında tek veya çok sayıda sert, ağrıs...
Bilateral anterior shoulder dislocation: A case report and a review of the literature
Dislocation is more often encountered due to multilateral mobility of the shoulder joint, its anatomic characteristics, and its being more exposed to traumas. Shoulder dislocations are often anterior and unilateral; thou...
Bir mevsimsel influenza epidemisi deneyimi
Amaç: Grip, dünyanın bütün bölgelerinde görülebilen, influenza virüsünün neden olduğu bir akut solunum yolu enfeksiyonudur. İnfluenza ile enfekte olan hastalarda, hastaneye yatışı gerektiren ve ölüme yol açabilen komplik...