Does the glycemic control and duration of diabetes affect Thyroid Dysfunction? A cross-sectional study from a tertiary hospital in Central Gujarat
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 8
Abstract
Abstract: Diabetes Mellitus (DM); a chronic metabolic syndrome and thryoid dysfunctions (TD) are the commonest endocrine disorder leading to high morbidity. Few studies have shown the association between the two. Hence this study was undertaken to understand association of thyroid dysfunction with the duration of diabetes and the degree of glycemic control. A cross-sectional study on 212 diabetic individuals was conducted in Sir Sayajirao General Hospital. All the patients were subjected to a detailed clinical history and examination including Hemogram and biochemical parameters [Random blood sugar (RBS), Fasting blood sugar (FBS), Post-prandial blood sugar (PP2BS), HbA1C and Thyroid profile (fasting): S.TSH, Free T3, Free T4]. The outcome measure was thyroid dysfunction and input variables included the duration of DM and glycemic control. Data was entered in MS Excel and analysed using Epi Info V3.5.4. The total prevalence of thyroid dysfunction (TD) was 24.2%among all 212 DM patients. Prevalence of TD was more in the group with poor glycemic control (82.5 %), which was higher than the group with good glycemic control (65.15 %).Prevalence of TD was greater (57.15%) in the population which had a longer duration of DM compared to those who had a shorter duration of DM (8.75%). There is a significant association of TD with duration of DM and poor glycemic control. It is necessary to screen all DM cases for TD for secondary prevention and also for primary prevention(early diagnosis and treatment); as thyroid dysfunction along with diabetes mellitus carries varyingly high rates of morbidity. Keywords:Thyroid dysfunction, Diabetes mellitus, association, glycemic control.
Authors and Affiliations
Dr. Keyur Brahme, Dr. Jaydeep Devaliya, Dr. Ishani Haldar, Dr. Mahendra Parmar, Dr Kalpita Shringarpure
Keywords
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