Does the use of Bispecteral Index reduce the oxidative stress in Endoscopic Retrograde Pancreoticocolangiography?
Journal Title: Journal of Surgery and Surgical Research - Year 2017, Vol 3, Issue 2
Abstract
Background: Endoscopic Retrograde Pancreoticocolangiography (ERCP) is performed for resolving cholestasis by sphincterotomy and/or stone extraction and is done with deep sedation or general anesthesia. Aim: Our aim was to evaluate the effects of the depth of anesthesia on oxidative stress provided via Bispecteral Index (BIS) monitorisation during the ERCP procedure by analyzing the biochemical parameters. And also was the effects of anesthesia depth on propofol consumption and postoperative sedation status. Methods: 50 patients undergoing ERCP procedure were randomly allocated in two groups. Propofol was given to provide the patients Ramsey sedation scale as 3 and 4 in Group R (n=25) patients whereas it was given to Group B (n=25) patients to provide BIS values between 65 to 85. The levels of total oxidant status (TOS), total antioxidant status (TAS), and OSI were measured. Hemodynamic signs, propofol consumption, postoperative recovery time were recorded. Results: TAS and OSI values were similar between the groups but TOS levels were significantly lower in Group B (p=0.027). Heart rate and mean arterial pressures of Group R were significantly higher than Group B. Propofol consumption and postoperative recovery time were smaller in Group B patients (p=0.001, p=0.000). Conclusion: In patients undergoing ERCP, using adequate sedation by BIS monitoring, may not only allow us to avoid unnecessary anesthetic drug consumption but also decrease the oxidant status.
Authors and Affiliations
Bakı Elif Doğan, Yılmaz Sezgin, Akıcı Özlem Çetin, Koca Halit Buğra, Sıvacı Remziye
Keywords
Related Articles
- EP ID EP350197
- DOI 10.17352/2455-2968.000045
- Views 76
- Downloads 0
Empty Nose Syndrome May Be the Chief Criminal Behind Many of the Worst Atrocities against Rhinologic Medical Staff in China
On Sep 3, 2012, several rhinology specialized medical staff members in Shenzhen Pengcheng Hospital were stabbed by a patient with blood-covered hands; on Oct 25, 2013, a chief physician of the otolaryngology department o...
Cystic Echinococcosis in the Liver: Nomenclature and Surgical Procedures
Cystic Echinococcosis (CE) is a zoonotic infection caused by larval form of the parasite Echinococcus granulosus. The adult tapeworm inhabit the small intestine of some carnivores (called definitive or final hosts), and...
Treatment of varicose veins – Surgery/ Laser
cAim of this study was to examine the results of treatment vv lower extremities to the appearance of improving the quality of life and the emergence of recurrence 1 year after operating (OP) and endovenous laser ablation...
Omental Cyst: An Atypical Presentation in a Child Masquerading Tubercular Ascites with Severe Acute Malnutrition and Sickle Cell Disease
Introduction: Omental cysts are rare abdominal lesions which may be difficult to diagnose. The incidence of cystic lesions is about 1 per 140,000 general hospital admissions and about 1 per 20,000 pediatric hospital admi...
Which Surgery in Geriatric Breast Cancer
Introduction: The improved living and environmental conditions have resulted in an increase in life expectancy with greater observation of breast cancer in elderly. The present study, through a retrospective analysis of...