Dosimetric comparison of non-coplanar three-dimensional conformal radiation therapy (nc3DCRT) planning and radio biologically optimized partial arc volumetric modulated arc therapy (VMAT) planning of unilateral brain tumours – A retrospective study
Journal Title: International Journal of Advances in Scientific Research - Year 2017, Vol 3, Issue 3
Abstract
Aim: To compare non-coplanar 3DCRT planning and partial arc VMAT planning dosimetrically for unilateral brain tumours. Introduction:Intensity modulated radiation therapyhas gainedwide popularity as a radiotherapy treatment of choice for many clinical sites. Volumetric modulated arc therapy is a kind of therapy in which rather than using multiple static fields at different gantry angles, one or multiple full or partial arcs are used for radiotherapy planning and treatment. Its ability to provide superior target coverage and better normal tissue sparing makes it a treatment of choice over conventional and 3DCRT radiotherapy planning techniques. But, on the same time volume of low dose region which can increase probability of secondary malignancy in VMAT planning is reported to be on the higher side. Our study compares various parameters of plan quality along with low dose volumes in the techniques under comparison. Materials and methods:10 anonymized patients with unilateral malignant brain tumours previously treated with nc3DCRT were selected for the study and planned with partial arc VMAT. Conformity Index, Homogeneity Index, Target Coverage, Doses to critical structures and normal brain were compared. Conclusion:In our study by using VMAT technique we were able to reduce doses to critical structures (Brainstem, optic nerves, and optic chiasm) significantly, got better target coverage along with lesser number of MUs per fraction and significant reduction in low dose volume and reduction in doses to contralateral normal structures including lesser amount of low dose volume.
Authors and Affiliations
Ashish Binjola, S. Megha Singh, Seema Sharma, V. Subramani, Subhash Gupta, Prateek Kumar, G. K. Rath
Keywords
Related Articles
- EP ID EP336101
- DOI 10.7439/ijasr.v3i3.4067
- Views 94
- Downloads 0
Assessment of effectiveness of spinal exercises and body mechanics on low back pain among post menopausal wome
Aim: To assessment of effectiveness of spinal exercises and body mechanics on low back pain among post menopausal women. Participants and setting: A quasi experimental non equivalent control group pretest post test desig...
Estimation of Heart Rate from Vocal Frequency Based on Support Vector Machine
Heart rate (HR) is one of the vital signs used to assess our physical condition; it would be beneficial if HR could easily be obtained without special medical instruments. In this study, a feature of vocal frequency was...
Antifungal Activities of bark extract of Calotropis procera (Ait.) R.Br. (Asclepiadaceae)
The present, manuscript deals with the antifungal activities of bark extract of Calotropis procera (Ait.) R.Br. a significant member of family Asclepiadaceae. The plant is glabrous herb or shrub with lower woody portion...
The Clinical and Hematological changes in Rabbits exposed to Melia azedarach fruits under experimental conditions
The study was conducted on 10 local breed rabbits, of 1-2 years age, of 1- 1.5 kg body weight.They were feed concentrated and green food, and left ad libitum for water, and kept in room of 20- 250C.The animals divided in...
Ethics in the study and practice of engineering: Pragmatic and intrinsic values in science and application
This paper will examine many of the ethical constraints and considerations that must be accounted for in the general field of engineering, and will also comment briefly on current trends in the recognition and definition...