Double Malignancies: A Rare Entity

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Double Malignancies: A Rare Entity

Journal Title: Surgery & Case Studies: Open Access Journal - Year 2018, Vol 1, Issue 1

Abstract

Patients which have diagnosed with a cancer, have a life time risk for developing another de novo malignancy depending on various inherited environmental and iatrogenic risk factors. Cancer victims could survive longer due to settling treatment modalities, and then would likely develop a new metachronous malignancy [1]. The incidence of multiple primary malignancies has not been rare at all. Screening procedures have especially been useful for the early detection of associated tumors, whereas careful monitoring of patients has treated for primary cancer, and then a good communication between patients and medical care team would certify not only an early detection for secondary tumors, but only finally & subsequently, an appropriate management [2]. Differentiation between multiple primary and multicentric cancers was addressed in the classification by Moertel CG [3]: I. MPMNs of Multicentric Origin a) The same tissue and organ. b) A common, contiguous tissue shared by different organs. c) The same tissue in bilaterally paired organs. II. MPMNs of Different Tissues or Organs III. MPMNs of Multicentric Origin Plus a Lesion (s) of a Different Tissue or Organ In 2002, However in ‘A review of the definition for multiple primary cancers in the United States’ classified the association of different cancers in two categories depending on the timing of their discovery [4]; a) Synchronous in which the cancers occur at the same time or within two months and b) Metachronous in which the cancers follow in sequence of more than two months apart. Vaamonde [5]. reckoned the time factor as six months. In 2005, International Agency for Research on Cancer working Group has come out with International Rules for Multiple Primary Cancers [6].

Authors and Affiliations

Subhashish Das

Keywords

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EP ID EP635113
DOI 10.32474/SCSOAJ.2018.01.000104
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