Down’s Syndrome- A Disease Caused By Genetic Alteration
Journal Title: Modern Approaches in Dentistry and Oral Health Care - Year 2018, Vol 2, Issue 2
Abstract
Down’s syndrome is the most common syndrome, medical professional encounters in day to day practice. It is a genetic disorder with a typical face profile and few classical intraoral features. Herein we report case and review on Down’s syndrome with facial features. Down syndrome is one of the commonest disorders with huge medical and social cost. DS is associated with number of phenotypes including congenital heart defects, leukemia, Alzheimer’s disease, Hirsch sprung disease etc. [1]. Down syndrome is a prevalent genetic disorder in intellectual disability in India. Its prevalence in tribal population is not known [2]. Down syndrome is one of the leading genetic causes of intellectual disability in the world. DS alone accounts 15-20% of ID population across the world [3,4]. An 8 year old male patient came to the department of oral medicine and radiology for routine dental check-up. Extra oral examination revealed characteristic facial profile with increased inter canthal distance (Figure 1). Intraoral examination revealed Gingiva was soft with deposits on the teeth, High arched palate, with depressed nasal bridge was seen (Figure 2). Macro glossia was also seen .Correlating the intraoral and extra oral findings a Provisional diagnosis of Down’s syndrome/ Trisomy 21 was given. Patient was referred to the respective departments of pedodontics for restoration of decayed teeth.
Authors and Affiliations
Vijayendranath Nayak S, Raghavendra Kini, Prasanna Kumar Rao J, Ashish S Shetty, Nidhin Kurian, Soumya Shetty
Keywords
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- EP ID EP607460
- DOI 10.32474/MADOHC.2018.02.000131
- Views 70
- Downloads 0
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