Doxycyclin induced esophageal injury: A Case series
Journal Title: Dicle Tıp Dergisi - Year 2013, Vol 40, Issue 2
Abstract
Some drugs have been known to damage to esophagus for a long time. Half of the cases reported are of tetracycline and its derivatives. The damage caused by these drugs is depends on the drug itself and the patient. In this paper we present 5 patients having diagnosed esophageal damage endoscopically after due to doxycyclin use. The mean age of the patients was 26 years. Three of them for acne and 2 for heir complaints gynecological infection were taking these drugs. Lesions were located at the middle in 4 cases and lover part in 1 patient. The common complaint was retrosternal pain and heartburn after taking the drug with insufficient water or without water. All the patients were relieved by symtomatic teratment. Esophageal damage is to be remembered in patients complaning sudden pain and difficult swallowing on doxycyclin treatment and endoscopic procedure should be employed for definition of diagnosis and evaluation of the severity of the damage. After treatment, endoscopic control is not necessary. Physicians must not forget to advice the patients to take these drugs with splendid amount of water. Key words: Doxycycline, esophagus damage, endoscopy
Authors and Affiliations
İsmail Demiryılmaz, İsmayil Yılmaz, Kemal Peker, Atalay Şahin, Nurdan Sekban
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