DPP METHOD FOR THE STUDY OF MELOXICAM IN PHARMACEUTICALS
Journal Title: European Journal of Pharmaceutical and Medical Research - Year 2017, Vol 4, Issue 9
Abstract
A planned method has been tested for Meloxicam estimation in dosage forms. This method based on using DPP with a DME versus Ag/AgCl as reference electrode. The best peak response was obtained at applied potential -1.2V in 0.1M acetate buffer at pH 4 and 0.01M KCl as supporting electrolyte. Calibration curve was suitable at a concentration variety between 0.1 and 0.8 μg.ml-1 with a correlation coefficient: r of 0.9995. The LOD and LOQ is found to be 0.024 and 0.079 μg.ml-1 respectively, RSD and overall mean recovery were 0.2 to 0.67% and 99.11% (n=5) respectively. The improvement method shows good sensitivity, selectivity; also it was applied to the determination of Meloxicam in pharmaceuticals.
Authors and Affiliations
Bayan H. A. Al-Ameri
Keywords
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