Drotaverine Hydrochloride Verses Hyoscine Butyl Bromide in Augmentation of Labour among Nulliparous Women
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 6
Abstract
Background: Prolonged labour is an important risk factor for both maternal morbidity and perinatal compromise.5 Minimizing the duration of labour without compromising fetomaternal wellbeing is a desirable outcome in all labour and delivery units.Since most of the prolonged labours are among the nulliparous women, the current study was done to compare the safety and efficacy of intravenous drotaverine hydrochloride against intravenous hyoscine butyl bromide in augmentation of labour among nulliparous women. Aims & Objectives AIM: To study and compare the efficacy and safety of Drotaverine hydrochloride and hyoscine-N-butyl bromide in the augmentation of labour among nulliparous women Objectives 1. To compare the efficacy of Drotaverine hydrochloride and Hyoscine-N butyl bromide in hastening cervical dilatation and thus in shortening the duration of labour. 2. To compare the side effects of both the drugs on the mother. 3. To compare the side effects of both the drugs on the newborn. Materials and Methods: The Government RSRM lying in hospital is a 500 bedded hospital dedicated to Obstetrics Gynaecology and Neonatology. It is a maternity and women’s health hospital attached to Stanley Medical College. On an average 10000 babies are delivered per year. Study Population: Nulliparous women admitted in spontaneous active labour to the labour ward at Government Raja Sir Ramasamy Mudaliar Lying in Hospital, Stanley Medical College from March 2015 - August 2015. These women were selected according to Inclusion and Exclusion criteria. Results: Drotaverine group when compared to control group showed a reduction in the duration of active phase by 50.92 minutes among nulliparous women which is statistically significant. Hyoscine group when compared to control group showed a reduction in the duration of active phase by 64.94 minutes among nulliparous women which is statistically significant. Drotaverine group when compared to Hyoscine showed a reduction in the duration of active phase by 14 minutes among nulliparous women which is statistically significant. Conclusion: Both Drotaverine hydrochloride and Hyoscine Butyl bromide is effective in shortening the duration of first stage of labour by virtue of faster cervical dilatation there by helping in augmentation of labour among the nulliparous women.
Authors and Affiliations
Dr. R. Fathima Hasan
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