Drug Absorption through the Skin – An Ancient and Modern View
Journal Title: International Journal of Ayurveda and Pharmaceutical Chemistry - Year 2019, Vol 0, Issue 0
Abstract
The skin is adapted to serve many different roles, since it is the major interface between the body and environment; Skin offers an accessible and convenient site for administration of medication. There is greatsignificance in targeting the skin as a site for drug application for systemic and local effect. The stratum corneum layer- outermost layer of the skin acts as barrier for many drugs. Modification or refinement of materials used may alter the absorption. So a thorough knowledge of dermal absorption is needed. In SushrutaSamhita the role of Thiryakdhamani’s in the absorption of drugs applied on skin surface, has been explained. He has mentioned the different time period taken by a drug, to enter through romakupa, Twacha, Raktaetc after Abhyanga. Through this paper an attempt is made to review briefly the absorption through skin in an ancient view, by comparing it to recent understanding of the skin absorption, in order to design safe and effective formulations to treat skin disorders.
Authors and Affiliations
Arpitha Shetty, Nithin Kumar
Keywords
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