Drug Induced Chronic Acquired Pure Red cell Aplasia in Adolescent boy
Journal Title: National Journal of Integrated Research in Medicine - Year 2011, Vol 2, Issue 3
Abstract
Acquired Pure red cell Aplasia (PRCA) is a disorder seen rarely in children and adolescents. Drugs like sodium valproate and carbamazepine have emerged as an important cause of acquired PRCA, when used for a long duration. Apart from the neurological side-effects, haematological side-effects in form of aplastic anemia and agranulocytosis are well-documented in carbamazepine therapy. The haematologic side-effects of carbamazepine, although not common, should nevertheless be borne in mind due to the serious, prolonged and sometimes even fatal consequences. Carbamazepine is a commonly prescribed drug in today’s scenario and it is important to be aware about its common and uncommon side-effects. We report a case of Carbamazepine induced pure red cell aplasia in an adolescent boy. Since, this drug induced PRCA is reversible if recognised early, it is worthwhile to be aware of this complication to prevent permanent morbidity due to generalised bone marrow hypoplasia. [Malipatil R A et al. NJIRM 2011; 2(3) :98-100].
Authors and Affiliations
Dr. Rajeev A Malipatil, Dr. Sunita Y Patil
Keywords
Related Articles
- EP ID EP40140
- DOI -
- Views 367
- Downloads 0
Histiocytic Necrotising Lymphadenitis (Kikuchi's Disease) [A 5 Year Histomorphological Study]
Background: Kikuchi’s disease is a rare, benign, self-limiting disease, mainly involving the lymph nodes of young people. The disease has unknown etiology. Clinical symptoms and basic investigations in a patient often...
Role of Mobile Phone in Spreading Hospital Acquired Infection: A Study in Different Group of Health Care Workers
Background: Use of mobile phones by Health Care Workers (HCWs) in the operation theatre (OT), Intensive Care Unit (ICU) and Critical Care Unit (CCU) may have serious hygiene consequences as these patients are more vuln...
Effect Of Celery (Apium Graveolens) Seeds Extract On Protease Inhibitor (Ritonavir) Induced Dyslipidemia
Objective: The present study was carried out to explore protective effects of ethanolic extract of Apium graveolens (celery seeds) on ritonavir, a protease inhibitor induced dyslipidemia. Materials & Methods: Thirty mi...
Effect of Amnioinfusion on Outcome of Neonates Born With Meconium Stained Amniotic Fluid
Background & Objective: Meconium stained amniotic fluid (MSAF) is associated with significant morbidity and mortality. Amnioinfusion can decrease complications of MSAF. The objective was to study role of Amnioinfusion...
Awareness about SuJok Therapy among medical students
Su = hand and Jok = foot. it is Korean words relating to a therapy that employs hands and feet as treatment areas for the whole body. Professor Park, Jae Woo is a Korean scientist and philosopher. Exploratory study was...