Drug Related Problems of Diabetic Nephropathy Patients in a Tertiary Hospital in Malaysia
Journal Title: Pharmacology and Clinical Pharmacy Research - Year 2016, Vol 1, Issue 2
Abstract
Patients with diabetic nephropathy (DN) are particularly vulnerable to drug related problems (DRPs) due to complex medication regimen and renal dysfunction. However, there was limited information regarding prevalence of DRPs among patients with DN in Malaysia. This research was conducted to determine the prevalence of DRPs among hospitalized patients with DN at tertiary hospital in Malaysia during June 2014-May 2015. This was a retrospective observational descriptive study that used patients medical records as data source. There were 104 subjects included in this study. The prevalence of DRPs among the included subjects was 74%. Most DRPs observed were from two categories, namely non-compliance to medication and adverse drug reactions (20.93% for both categories). These categories were followed by the category of unnecessary drugs (16.28%), too low dose (15.81%), inappropriate drugs (11.16%), untreated indication (10.23%) and too high dose (4.65%). The prevalence of DRP was high among DN patients, thus pharmacists are encouraged to perform comprehensive medication review to improve health outcomes and enhance patients safety.
Authors and Affiliations
Dika P. Destiani, Athirah Ghazali
Keywords
Related Articles
- EP ID EP352049
- DOI -
- Views 126
- Downloads 0
The Effect of Anti-Tuberculosis Drugs on the Effectiveness of Anti-Retroviral Therapy in HIV-AIDS Patients
Tuberculosis is the most common opportunistic infection and a leading cause of death among patients who infected by Humman Immunodeficiency Virus (HIV) in developing countries. The purpose of this study was to determine...
Phaleria macrocarpa (Boerl.) Scheff Fruit: A Potential Source of Natural Antioxidant
Phaleria macrocarpa (Scheff.) Boerl is originated from Papua Island, Indonesia. There have been only limited attempts to explore the biological properties of this plant in relation to their medicinal use. This study aime...
Anti-proliferative Activity of Crotalaria pallida Aiton on MCF-7 Breast Cancer Cells
Crotalaria pallida Aiton (C. pallida Aiton) is empirically used as dietary supplement to treat cancer by the people of North Sulawesi. However, its scientific pharmacology activity has not been explored yet. Therefore, t...
Local Hemostatic Activity of Psidium guajava Leaves in Swiss Webster Mice
Psidium guajava (P. guajava) leaves have been empirically used to stop bleeding. Tannin, one of this plant’s secondary metabolites, may contribute to this activity. However, information regarding its pharmacologicy activ...
Hepatotoxicity Effects of Alcohol Consumption during Paracetamol Therapy of Malaria Patients
The risk of paracetamol induced hepatotoxicity could increase with alcohol consumption. Paracetamol was usually given to tropical malaria patients to treat fever. The aim of this study was to determine the hepatotoxicity...