Dry eye syndrome in reproductive age group women on oral contraceptives
Journal Title: Indian Journal of Clinical and Experimental Ophthalmology - Year 2018, Vol 4, Issue 2
Abstract
Purpose To investigate the correlation between dry eye syndrome with Androgen profile and its relation with use of Oral Contraceptives in females within child bearing ageMaterials and Methods Study consists of 100 healthy women between 2049 years out of which 50 were on OCPs Oral contraception pills and rest 50 as control group were not taking any hormonal contraceptives Androgen profile was carried out by Enzyme Immuno Assay on blood samples which were collected during 6th to 8th day Early follicular phase of menstrual cycle The tear secretion was measured by Schirmers test Qualitative parameter of tear film was measures by Tear Breakup time TBUT Statistical analysis was done to determine the correlation between tear film parameters and androgen profile and oral contraceptive useResults Our result demonstrate that androgen profile 40serum testosterone and DHEA levels41 were decreased significantly PConclusion Our findings shows that androgen levels decrease in women taking oral contraceptives These results support that androgen deficiency and oral contraceptives may be an important etiological factor in pathogenesis of dry eye syndrome in premenopausal womenKeywords Androgen profile Schirmer39s test Tear film breakup time Dry eye syndrome Oral contraceptives
Authors and Affiliations
Manoj Tyagi, Praveen Khare, Amita Sharma
Keywords
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- EP ID EP474231
- DOI 10.18231/2395-1451.2018.0058
- Views 113
- Downloads 0
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