Early and late onset psoriasis: A clinical study
Journal Title: MedPulse -International Medical Journal - Year 2015, Vol 2, Issue 10
Abstract
Background: It has been postulated that two clinical subtypes of psoriasis, namely the “early onset” and the “late onset” can be characterized based upon the age of onset. However precise data to differentiate the two clinical subtypes of psoriasis are not available. Objective: To investigate the clinical characteristics of early and late onset psoriasis in the Mauritian patient. Methodology: A cross-sectional study of consecutive 55 patients of psoriasis was carried out at the Skin Outpatient department of a regional hospital in Mauritius. The Case study method was used to collect the clinical data and was recorded in a comprehensive Case Record Form. The data was statistically analyzed using SPSS 22 (Statistical Package for the Social Sciences) software. Results: A bimodal distribution of onset of psoriasis was observed with peak occurring at the age of 20-30 years in 12 (21.8%) patients and 49-59 years in 24 (43.6%) patients; 27 (49.1%) patients had onset < 40 years; 28 (50.9%) patients had onset ≥ 40 years. In Early onset psoriasis significant co-morbidities were present in 22/27 (66.7%) of patients. In late onset psoriasis 22/28 (78.6%) were male. Out of 33 patients with nail involvement 26 (78.8%) were male as compared to 7 (21.2%) female patients, which was significant. Total Body Surface Area larger than 10% was observed in 12 (44.4%) in early onset psoriasis as compared to 6 (21.4%) in late onset psoriasis but was statistically not significant. Conclusions: Psoriasis has a bimodal distribution of age of onset, a higher incidence of co-morbidities in the early onset and a male preponderance in late onset subtype. Men have a higher incidence of nail involvement but a lesser incidence of psoriatic arthritis as compared to women.
Authors and Affiliations
Yogesh M Shah, Alka D Gore, Bibi Kaushur D Khodaboccus
Keywords
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