Early Detection of Abnormal Left Atrial and Left Ventricular Coupling, Using Two-dimensional Speckle Tracking Echocardiography in Patients with Preserved Left Ventricular Ejection Fraction
Journal Title: Cardiology and Angiology: An International Journal - Year 2016, Vol 5, Issue 4
Abstract
Aims: The aim of this study was to detect the abnormalities of left atrial (LA)-left ventricular (LV) coupling using two-dimensional speckle tracking echocardiography in patient with preserved LV ejection fraction. Methods: A total of 177 asymptomatic patients with preserved LV ejection fraction were studied. Global LV longitudinal peak strain (GLS) and peak LA longitudinal strain during systole (PALS) were measured. The ratio of E/Ea to PALS was used as an index of LA stiffness. Results: The patients were classified into 2 groups according to the GLS: impaired group (n=81; GLS>-18%) and normal group (n=96; GLS≤-18%). Both GLS and PALS were reduced in the impaired group (p<0.001). LA stiffness was increased in the impaired group (p<0.05). In the normal group, there was no significant correlation between GLS and LA volume index. There was no significant correlation between GLS and LA stiffness. In the impaired group, GLS significantly correlated with correlated with the LA stiffness (r=0.50, p<0.001). Similarly, GLS significantly correlated with LA volume index (r=0.36, p<0.001). Conclusions: In patients with preserved longitudinal LV systolic function, LA structure and function are preserved. However, LA structure and function are rapidly impaired in patients with reduced longitudinal LV systolic function. LV longitudinal systolic dysfunction may cause the LA wall to become stiffer rapidly.
Authors and Affiliations
Yoshikazu Ohara, Yuki Yoshimura, Yohko Fukuoka, Atsuko Furukawa, Hosogi Shingo, Katsuhito Yamamoto
Keywords
Related Articles
- EP ID EP327674
- DOI 10.9734/CA/2016/29072
- Views 82
- Downloads 0
Factors Influencing the Risk of Death among Patients with Heart Failure
The purpose of this study was to investigate the impact of risk factors on the death of patients with heart failure in a cohort of patients hospitalized with heart failure disease. In this paper we used chi-square tests...
Catheter Ablation of Atrial Fibrillation: Three-dimensional Transesophageal Echocardiography Provides an Excellent Overview over the Pulmonary Vein Anatomy Facilitating Radiofrequency and Cryoablation Procedures
Background: Catheter of atrial fibrillation is still challenging because of the high degree of variability of the pulmonary vein anatomy. Therefore, 3D imaging systems are frequently used prior to an ablation procedure....
Effect of Short Systemic Intermittent Hypoxia on Systemic Hemodynamics Blunted in Cutaneous Microcirculation
Background: Hypoxic stimulus induces a homeostatic disruption to enhance physiological adaptation. Blood flow in the microcirculation plays an important role in maintaining healthy tissues by delivering oxygen. The cutan...
Can We Predict Preeclampsia?
Hypertensive disorders in pregnancy are a leading cause of peripartum morbidity and mortality. Preeclampsia is a heterogeneous maternal syndrome. Large studies have pointed out the association of impaired spiral artery...
Right Atrial Myxoma Complicated by Pulmonary Thromboembolism: A Case Report and Review of Literature
Primary cardiac tumors are rare with myxoma being the most common benign cardiac tumor. They are usually sporadic, affecting left atrium and frequently occur in women. They are known to cause valvular obstruction, thromb...