Early Detection of Abnormal Left Atrial and Left Ventricular Coupling, Using Two-dimensional Speckle Tracking Echocardiography in Patients with Preserved Left Ventricular Ejection Fraction
Journal Title: Cardiology and Angiology: An International Journal - Year 2016, Vol 5, Issue 4
Abstract
Aims: The aim of this study was to detect the abnormalities of left atrial (LA)-left ventricular (LV) coupling using two-dimensional speckle tracking echocardiography in patient with preserved LV ejection fraction. Methods: A total of 177 asymptomatic patients with preserved LV ejection fraction were studied. Global LV longitudinal peak strain (GLS) and peak LA longitudinal strain during systole (PALS) were measured. The ratio of E/Ea to PALS was used as an index of LA stiffness. Results: The patients were classified into 2 groups according to the GLS: impaired group (n=81; GLS>-18%) and normal group (n=96; GLS≤-18%). Both GLS and PALS were reduced in the impaired group (p<0.001). LA stiffness was increased in the impaired group (p<0.05). In the normal group, there was no significant correlation between GLS and LA volume index. There was no significant correlation between GLS and LA stiffness. In the impaired group, GLS significantly correlated with correlated with the LA stiffness (r=0.50, p<0.001). Similarly, GLS significantly correlated with LA volume index (r=0.36, p<0.001). Conclusions: In patients with preserved longitudinal LV systolic function, LA structure and function are preserved. However, LA structure and function are rapidly impaired in patients with reduced longitudinal LV systolic function. LV longitudinal systolic dysfunction may cause the LA wall to become stiffer rapidly.
Authors and Affiliations
Yoshikazu Ohara, Yuki Yoshimura, Yohko Fukuoka, Atsuko Furukawa, Hosogi Shingo, Katsuhito Yamamoto
Keywords
Related Articles
- EP ID EP327674
- DOI 10.9734/CA/2016/29072
- Views 86
- Downloads 0
A Four-year Study of Chronic Patients’ Information Integration in Dental and Medical Documentation in a Secondary Care Setting
Integrated health documentation captures, imports and exports relevant extract of patient’s longitudinal health information record. Especially documenting patients’ chronic disease data in dental documentation system is...
Cerebrovascular Diseases and Associated Risk Factors in WHO Eastern Mediterranean Countries
Background: In the WHO Eastern Mediterranean region, nearly one million deaths are caused by cardio-vascular diseases every year. During the last decade, the number of deaths caused by stroke increased by 23%. Most cardi...
Central Venous Catheter in Obese Patient May Even Cause Cor Pulmonale
Introduction: Sometimes the needless usage of central venous catheter, conflicting with indications, has been witnessed. Unfortunately, incidence of axillary-subclavian venous thrombosis has risen gradually because of in...
Delayed Heart Rate Recovery and Exaggerated Blood Pressure Response during Exercise Testing in Nigerian Normotensive Diabetics
Aim: The aim of this study was to identify the clinical profile of normotensive Type 2 diabetes mellitus (T2DM) with exercise related exaggerated systolic blood pressure (ESBP) and delayed heart rate recovery (HRR); and...
PAS Exfoliation in Watermelon and Aloe Vera Recuperate Glycogen in Heart Tissue Damaged by Cadmium in Adult Wistar Rats (Rattus novergicus)
Cadmium (Cd) is a major concern of World Health Organization for public health and is a highly toxic element which is naturally present in all parts of the environment. Watermelon contributes nutritional agents as antiox...