Early Outcomes of Transoral Laser Microsurgery for T1-T2 Oropharyngeal Cancer
Journal Title: Asian Journal of Pharmaceutical Research and Health Care - Year 2018, Vol 10, Issue 4
Abstract
The optimal treatment strategy for oropharyngeal carcinoma is highly debated. However, growing evidence supports the use of minimally invasive techniques, such as Transoral Laser Microsurgery (TLM), as a first-line treatment modality for these carcinomas. The purpose of our study was to assess the efficacy and safety of TLM for the treatment of early oropharyngeal carcinomas. This is a prospectively observational study of 30 early stages (T1/T2) oropharyngeal cancer patients who underwent transoral laser microsurgery from January 2016 to March 2019. 30 patients of early-staged oropharyngeal carcinoma (19 tongues, 5 soft palates, 4 tonsils and 2 posterior pharyngeal walls) were included in this study. 19 (63.3%) patients were male and 11 (36.7%) were female. The mean age was 54.8 years (± 10.6 years). 76.7% tumours are T1 and 23.3% T2. The bleeding complications occurred in 2 patients. The most frequent complication of TLM was bleeding. 30% of patients had normal voices and a further 63.3% had only mild or moderate voice change. At their last follow up, no patients had any difficulty in breathing or swallowing. TLM is a safe, minimally invasive and effective method in the treatment for early oropharyngeal cancer.
Authors and Affiliations
Tran Phan Chung Thuy, Nguyen Thanh Tuan
Leadership and Task Shifting to Address the Challenges of Antimicrobial Resistance in South Africa
Antimicrobial resistance is a complex problem interconnected with many factors, such as overuse and misuse of antimicrobials across the world, especially in Low- and Middle-Income Countries (LMICs). To overcome this, the...
Comparative Experimental Studies of Few L-Type and T-Type Ca2+ Channel Blockers Against In-Ovo and In-Vitro Models of Angiogenesis
Angiogenesis is the development of new blood vessels from pre-existing one. The ion-channels on endothelium plays vital role in cell proliferation and related angiogenesis. We aimed to investigate the effects of L-type (...
Review of Adoption of Disruptive Innovative Practices in Medical Tourism in India
The Indian Medical Tourism Industry is significantly adding nearly 3% to the total size of the healthcare sector of India. Surgical techniques and healthcare technologies have undergone revolutionary changes in the past...
A Comparative Study to Assess the Relationship of Placental Weight and Fetal Outcome among Normal and Anemic Mothers Admitted in Tertiary Care Hospital Karad
Severe anemia during pregnancy is a potentially hazardous hematological disorder. According to a World Health Organization (WHO) report teh global prevalence of anemia among pregnant women is 55.9%. In India, teh highest...
A Study to Assess the Effectiveness of Ice Application on Pain Response Prior to Intravenous Procedures among Children at Tertiary Care Hospital
Children fear the most for pain from intravenous procedures during their hospitalization. The procedural pain is worse TEMPthan the illness itself. Ice is a convenient topical refrigerant modality which can be used to re...