Edematous striae distensae in nephrotic syndrome
Journal Title: Journal of Health and Social Sciences - Year 2016, Vol 1, Issue 2
Abstract
CLINICAL IMAGES IN MEDICINE A 19 year old male was evaluated for swelling over face and body for 3 months. Examination revealed swelling over face, pitting edema feet. The patient was found to have significant proteinuria (3.1 gram/24 hours) and red blood cells (RBCs) were seen on urine examination. In view of deteriorating renal function (creatinine 3.1 mg/dL), renal biopsy was done which revealed focal segmental glomerulosclerosis. The patient had been on steroids (prednisolone 60 mg/day) for previous one month. Presently large edematous and distended striae over abdomen (Fig. 1) and lower limbs were seen (Fig. 2 and 3) which had developed after steroid use. Striae distensae are common dermatological lesions which may result from a multitude of causes. The various factors implicated in the causation of these lesions include use of steroids, Cushing syndrome, pregnancy, weight gain, obesity, adolescence and racial factors. Apart from the abdomen they may occur at the breasts, buttocks, thighs, knees and calves [1]. Striae rubrae are erythematous red and flat lesions which may precede the hypopigmented striae distensae. The possible mechanism of their genesis is related to stretching of the skin and its mechanical effects. Edematous striae distensae, however, are uncommon and have been described in underlying nephrotic syndrome [2–4]. Although the abdominal striae are a well-recognised complication of steroid use, however the edema associated with protein loss in glomerular disease can further accentuate the appearance of these striae as noted in our case.
Authors and Affiliations
Swarup Kumar Patnaik, Sandeep Lamoria, Vishal Sharma
Keywords
Related Articles
- EP ID EP216132
- DOI 10.19204/2016/dmts18
- Views 104
- Downloads 0
Spiritual well-being in the 21st century: It is time to review the current WHO’s health definition
Over the years, some critics argue that the dimension of spiritual well-being was missing from the World Health Organization’s (WHO) definition of health. Nevertheless, although the WHO’s definition has been criticized o...
Case Reports: The core of practice-based evidence
A case report is a type of scientific paper that describes a patient-centred clinical pathway, which depends on medical doctor’s viewpoint, clinical insights and professional skills [1]. Case reports are particularly use...
Home management of malaria among caregivers of under-five children in Owo, Ondo State, Nigeria
Introduction: Home management of fever by caregivers is particularly relevant for ensuring effective care to under-five children in Sub-Saharan countries with high-transmission of malaria like Nigeria. Our study aimed to...
A case of asymptomatic ST segment changes in cyclist with two myocardial bridges
A 65-year-old male regularly involved in competitive cycling came to our sports medicine laboratory for the annual mandatory pre-participation screening. Cycling screening protocol includes a cardiological examination, b...
Bacterial profile and antibiotic susceptibility pattern of adult lower respiratory tract infections in Colombo, Sri Lanka
Introduction: Lower respiratory tract infections (LRTIs) remain the deadliest communicable disease around the world. This study was conducted to identify the bacterial etiology of LRTIs among patients who attended the Ce...