Serum homocysteine levels in patients with nonalcoholic fatty liver disease

Background and rational for the study. Nonalcoholic fatty liver disease (NAFLD) is regarded as the hepatic component of insulin resistance (IR) syndrome, but data on serum homocysteine (HCY) are limited. The aim of the s...

Combined high-fat diet and sustained high sucrose consumption promotes NAFLD in a murine model

Background. The study of NAFLD in humans has several limitations. Using murine models helps to understand disease pathogenesis. Aim. Evaluate the impact of 4 different diets in the production of NAFLD with emphasis on a...

Retinoid X Receptor α-Dependent HBV Minichromosome Remodeling and Viral Replication

Background and aim. The HBV covalently closed circular DNA (cccDNA) is organized into a minichromosome in the nuclei of infected hepatocytes through interactions with histone and nonhistone proteins. Retinoid X receptor...

Distribution of HCV genotypes and HCV RNA viral load in different regions of Mexico

Background and aim. To identify the geographic distribution of hepatitis C virus (HCV) genotypes and HCV RNA viral load in a large number of HCV-infected carriers in Mexico. Methods. Patients with chronic hepatitis C (n...

Mean platelet volume is a useful indicator of systemic inflammation in cirrhotic patients with ascitic fluid infection