EDTA Dependent Pseudothrombocytopenia In A Patient With Scrub Typhus - A Case Report
Journal Title: BMH Medical Journal - Year 2016, Vol 3, Issue 1
Abstract
We report a case of EDTA induced pseudothrombocytopenia (EDTA-PTCP) in a patient with scrub typhus who was referred as a case of pyrexia of unknown origin (PUO) with marked thrombocytopenia and treated with platelet transfusion. Blood smear examination revealed numerous platelet aggregates. CBC analysis using citrate and lithium-heparin as anticoagulants as well as a peculiar WBC histogram aided in prompt diagnosis of the condition. The prevalence of EDTA-PTCP in general hospital population is approximately 0.1%. It is usually not associated with hemorrhagic manifestations. Hence cases of thrombocytopenia should be carefully evaluated to rule out this form of artefactual thrombocytopenia. Timely diagnosis of this innocuous but misleading in vitro phenomenon can save the patient from unnecessary transfusions and invasive procedures.
Authors and Affiliations
Bhavya P Mohan, S Sheeja, KK Prabhalekshmy
Keywords
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