Efek Hepatotoksisitas Ekstrak Etanol Herba Kompri (Symphytum officinale L.) Terhadap Hewan Uji Kelinci (Oryctolagus cuniculus) Dengan Parameter SGOT dan SGPT
Journal Title: Biogenesis: Jurnal Ilmiah Biologi - Year 2014, Vol 2, Issue 1
Abstract
This study aims to determine the hepatotoxic effects of extract ethanol Herba Comfrey the rabbit test animals by measuring levels of SGOT and SGPT. This study used 12 rabbits were divided into 4 groups. The control group (-) given Na.CMC 1% w/v, group I, II, and III were given suspensions of extract ethanol Herba Comfrey with each concentration of 2% w/v, 4% w/v and 8% w/v for 7 days. The results showed that the extract ethanol Herba Comfrey with concentration of 2% w/v, 4% w/v, and 8% w/v effects can cause hepatotoxicity. It is showed from the increase in the average SGOT value in rabbits at 13.96 U/L, 20.63 U/L and 37.13 U/L. and SGPT value of 20.73 U / L, 32.4 U / L and 44.66 U / L. extract Ethanol Herba Comfrey with concentration 8% w / v causes an increase in SGOT and SGPT concentrations higher than the other, and accelerate the liver damage or hepatotoxicity. The higher the concentration, the greater the effect.
Authors and Affiliations
Norma Norma, Ulfa Triyani, Syamsidar Usman
Keywords
Related Articles
- EP ID EP276596
- DOI 10.24252/bio.v2i1.462
- Views 255
- Downloads 0
Isolasi Bakteri Pendegradasi Minyak Solar Dari Perairan Teluk Pare-Pare
Penelitian ini bertujuan untuk memperoleh bakteri yang terdapat di Pelabuhan Pare-Pare yang mampu mendegradasi minyak solar. Penelitian dilaksanakan di Laboratorium Mikrobiologi Jurusan Biologi Fakultas Sains dan Teknolo...
Isolasi dan Pengukuran Aktivitas Enzim Bromelin dari Ekstrak Kasar Bonggol Nanas (Ananas comosus) pada Variasi Suhu dan pH
This study was conducted to isolate the bromelain enzyme from pineapple weevil (Ananas comosus) and measure the protein and enzyme activity of bromelain with gelatin substrate. Research stage involves determining the pro...
Kajian Potensi Kualitas Kayu Melalui Uji Marka Anatomi Pada Tanaman Puspa (Schima wallichii (DC.) Korth. Sebagai Tanaman Revegetasi Lahan Pascatambang
Revegetasi merupakan salah satu upaya untuk memulihkan lingkungan tercemar. Beberapa tanaman telah dijadikan sebagai tanaman revegetasi karena termasuk kepada jenis cepat tumbuh (Fast Growing Species) dan adaptif pada la...
Pewarisan Sifat Ketahanan Hidup dan Karakter Fenotipik Melon (Cucumis melo L. “TALITA” & “TANIA”) Hasil Persilangan Backcross dan Testcross Induk Tacapa Pada Kondisi Karst Secara In-Vivo
Melon (Cucumis melo L.) is one of the fruits commodity priorities and require more attention. Plant breeding efforts led to improved varieties like TACAPA .TACAPA is a new melon cultivar derived from crosses between ♀ PI...
Pemanfaatan Sari Pati Umbi Gadung (Dioscorea hispida Dennst) Untuk Koagulasi Lateks Karet Alam (Hevea brasiliensis)
Telah dilakukan penelitian pemanfaatan sari pati umbi gadung (Dioscorea hispida Dennst) terhadap koagulasi lateks karet alam (Hevea brasiliensis) yang bertujuan untuk mengetahui pengaruh beberapa konsentrasi sari pati um...