Effect of Abo blood groups and Haemoglobin variants on the prevalence of mild Falciparum malaria
Journal Title: INTERNATIONAL JOURNAL OF CURRENT RESEARCH - Year 2015, Vol 7, Issue 9
Abstract
There are conflicting reports on the effect of ABO blood groups and/or haemoglobin variants on the prevalence of falciparum malaria. The present study examined the effect of ABO blood groups and/or haemoglobin variants on the prevalence of uncomplicated (mild) falciparum malaria in a hyperendemic area. A total of 486 malaria positive patients and 486 controls of age ≥16 years were screened for this study. Malaria parasite test, ABO blood group antigens test and haemoglobin genotype were carried out using standard laboratory techniques. There was no significant relationship between ABO blood groups and malaria (χ2 = 1.14, df = 3, p = 0.767). However, malaria varied significantly with hemoglobin variants (χ2 = 27.09, df = 5, p < 0.001). When combined, a significant association was only observed in the distributions of blood types A, B and O between AA and AS variants (χ2 = 7.931, df = 2, p = 0.019) in the malaria group. Proportion of malarial infection increases as follows: O+AS(0.345) < B+AS(0.424) < A+AS(0.468) < A+AA(0.489) < B+AA(0.55) < O+AA(0.568). While group O individuals who have HbAS genotype are the most resistant to malaria, group O who have HbAA are the most susceptible. This study shows that in this malaria hyperendemic area, mild falciparum malaria is influenced by haemoglobin genotype but not by ABO blood type.
Authors and Affiliations
Igbeneghu, C Alabi, T, Olisekodiaka, J. M . , Adedokun, A. S . , Odaibo, A. B. .
Keywords
Related Articles
- EP ID EP406023
- DOI -
- Views 123
- Downloads 0
A COMPARATIVE STUDY ON EFFICACY OF GAIT PARAMETERS IN CHRONIC-STROKE SURVIVORS USING FUNCTIONAL TASK-ORIENTED INTERVENTION VERSUS BOBATH INTERVENTION
Background: The rising burden of stroke, especially in low-income and middle-income countries, leads us to propose a worldwide goal for stroke: a 2% reduction each year over and above that which may happen as a result of...
Acinic cell carcinoma of parotid gland- A case report
The Acinic cell carcinoma represents about 1% of all salivary gland tumors. Between 90 and 95% of these tumors are found in the parotid gland. Clinically if the site is parotid gland, it may resemble a pleomorphic adeno...
Comparative evaluation of laser, Cyanoacrylate and laser with Cyanoacrylate in the treatment of dentine hypersensitivity – A clinical study
Aim: To evaluate and compare the clinical efficacy of laser, cyanoacrylate and laser with cyanoacrylate in the treatment of dentine hypersensitivity. Materials and Methods: The study sample comprised of 150 sites out of...
A rare case of aneurysmal bone cyst of the calcaneum
Aneurysmal bone cyst (ABC) is a benign solitary bone lesion of unknown etiology. ABCs mainly occur in the long bones but only rarely in the bones of the feet. Few cases of ABC involving the calcaneum have been reported.W...
Smart materials in dentistry
Change is inevitable. With the advent of time, several changes have occurred in the field of dentistry as well. The era of smart materials has changed the face of dentistry drastically. Smart materials are materials that...