EFFECT OF ANTIOXIDANTS IN PRE ECLAMPSIA WOMEN AT INCREASED RISK
Journal Title: International Journal of Medical Research & Health Sciences (IJMRHS) - Year 2013, Vol 2, Issue 2
Abstract
Preeclampsia is a leading cause of maternal and neonatal mortality and morbidity. It is a complex syndrome of undetermined etiologic origin, usually diagnosed during second half of pregnancy. Elevated levels of oxidative lipid derivatives and reduced antioxidants in the circulation of preeclamptics may contribute to endothelial damage. There is good evidence for a significant increase in the levels of malondialdehyde in plasma and erythrocytes. Group I: Normotensive nonpregnant women (control), Group II: Pregnant women with normal blood pressure, Group III: Preeclamptic (pretreatment), women Preeclamptic women were subdivided into Group IIIA: Pre eclamptic women supplemented with Vitamin E (n=20), Group IIIB: Preeclamptic women supplemented with Omega 3 Fatty Acid, Group IIIC: Preeclamptic women supplemented with Vitamin E 400mg + Omega 3 Fatty Acid. Serum SOD, MDA, GPx, GSH levels were measured in all groups and compared with pre treatment and post treatments results by using the one way ANOVA followed by the Tukey – HSD procedure. Our results showed that supplementation of Vitamin E, Omega 3 fatty acid alone and in combination has significantly increased antioxidant enzyme status and significantly decreased oxidative stress when compared to unsupplemented patients(P< 0.001).
Authors and Affiliations
Vijayalakshmi B| Department of Physiology, Meenakshi Medical College, Kanchipuram, Tamilnadu, India Corresponding author email: vijayalakshmib2@gmail.com, Kondam Ambareesha| Department of Physiology, Meenakshi Medical College, Kanchipuram, Tamilnadu, India, Kayalvizhi E| Department of Physiology, Meenakshi Medical College, Kanchipuram, Tamilnadu, India, Qairunnisa S| Department of Physiology, Meenakshi Medical College, Kanchipuram, Tamilnadu, India, Revathi M| Department of Physiology, Meenakshi Medical College, Kanchipuram, Tamilnadu, India, Chandrasekhar M| Department of Physiology, Meenakshi Medical College, Kanchipuram, Tamilnadu, India
Keywords
Related Articles
- EP ID EP10962
- DOI -
- Views 376
- Downloads 21
ECTOPIC PREGNANCY AFTER SEQUENTIAL EMBRYO TRANSFER: REVIEW OF 22 CASES
Objective: To assess the prevalence of ectopic pregnancy among women who conceived with assisted reproductive technology and to see if there is increased risk after sequential embryo transfer. Methods: The ectopic preg...
Influence of climatic parameters on the distribution of air pollutants and public health in Annaba (East of Algeria)
This study is destined to show the relationship that exists between atmospheric pollution from automobile origins and the cases of hospital admissions for cardiovascular causes (ACV) and pulmonary infections (AP) in Ann...
Role of prebiotic and probiotic in the management of chronic kidney disease patients
Chronic Kidney disease is more common in Indian population today. Hence the need of medications for chronic kidney disease also increased now a days. This study is designed to investigate the role of Prebiotics and prob...
Sero- Epidemiological trends of Dengue Fever in Jammu Province of J&K State
Dengue, an arthropod-borne arboviral disease is becoming a major public health concern, both in the tropical and subtropical regions of the world. In view of exponential increase in dengue positive cases reported in 201...
Sonographic Assessment of Parotid and Submandibular Glands in Patients Undergoing 3D Conformal Radiotherapy
The aim of this study was to evaluate sonographic changes in parotid and submandibular salivary glands in patients undergoing radiotherapy for head and neck malignancies. In addition, salivary changes subsequent to radi...