Effect of Aqueous Extracts of some Ayurvedic Medicinal Plants on Tissues Involved in Glucose Homeostasis in vitro
Journal Title: International Journal of Diabetology & Vascular Disease Research (IJDVR) - Year 2015, Vol 3, Issue 6
Abstract
Aqueous extracts of some antidiabetic Ayurvedic plant treatments such as Trigonella foenum-graecum Linn (TFG), Pterocarpus marsupium Roxb (PM), Gymnema sylvestre R.Br (GS) and Curcuma longa Linn (CL) were tested for their biological effects on glucose uptake by mouse muscle tissue and insulin secretion from mouse pancreas under both basal and hyperglycemic culture conditions. The results indicate that none of these treatments have a significant effect on either glucose uptake by muscle or insulin secretion from the pancreas under basal conditions. Under hyperglycemic conditions all treatments except GS demonstrate significant effects on glucose uptake by muscle tissue, and all treatments were effective at increasing insulin secretion from pancreas. This suggests that all these plant treatments enhance glucose homeostasis by stimulating either insulin secretion (GS) or enhancing glucose uptake (TFG) or activating both (CL and PM).
Authors and Affiliations
James R. McFarlane
Keywords
Related Articles
- EP ID EP198921
- DOI 10.19070/2328-353X-1500021
- Views 80
- Downloads 0
A Non-Invasive Glucose Estimation in Saliva Samples by using Pre Column Derivatised RP-HPLC
Diagnostic devices available in the market to measure blood glucose level which requires blood as diagnostic body fluid. Hence, necessity arises to find some non-invasive diagnostic mean to measure body glucose level fre...
Indirect Cost Of Diabetes In The Arab Region
Diabetes is one of the chronic diseases with a high prevalence and consequently a substantial socio-economic burden in Arab countries. In this paper, we propose for the first time an estimation of the indirect economic c...
Relationship Between Retinal-Renal Complications Among Type 2 Diabetic Subjects in India
Aim: The aim of this study was to determine the relationship between retinal-renal complications among type 2 diabetic subjects in India. Subjects and Methods: A total of 502 subjects with type 2 diabetes who underwent F...
Associations of Binge Drinking and Smoking with Type 2 Diabetes among Adults in California: Age and Race Differences
Objective:The incidence of type 2 diabetes (T2D) is rising rapidly in the world. Findings focusing on the impact of two main lifestyle factors, smoking and alcohol consumption, on T2D were mixed. We aimed to estimate the...
A Study to Evaluate Association of Celiac Disease with Insulin Dependent Diabetes and Hypothyroidism in North-West Rajasthan
Objective: To study association of Celiac Disease with Insulin Dependent Diabetes and Hypothyroidism in young adults in North-Western Rajasthan. Method: Total eighty-seven newly diagnosed adult patients of celiac diseas...