Effect of Aqueous Extracts of some Ayurvedic Medicinal Plants on Tissues Involved in Glucose Homeostasis in vitro
Journal Title: International Journal of Diabetology & Vascular Disease Research (IJDVR) - Year 2015, Vol 3, Issue 6
Abstract
Aqueous extracts of some antidiabetic Ayurvedic plant treatments such as Trigonella foenum-graecum Linn (TFG), Pterocarpus marsupium Roxb (PM), Gymnema sylvestre R.Br (GS) and Curcuma longa Linn (CL) were tested for their biological effects on glucose uptake by mouse muscle tissue and insulin secretion from mouse pancreas under both basal and hyperglycemic culture conditions. The results indicate that none of these treatments have a significant effect on either glucose uptake by muscle or insulin secretion from the pancreas under basal conditions. Under hyperglycemic conditions all treatments except GS demonstrate significant effects on glucose uptake by muscle tissue, and all treatments were effective at increasing insulin secretion from pancreas. This suggests that all these plant treatments enhance glucose homeostasis by stimulating either insulin secretion (GS) or enhancing glucose uptake (TFG) or activating both (CL and PM).
Authors and Affiliations
James R. McFarlane
Keywords
Related Articles
- EP ID EP198921
- DOI 10.19070/2328-353X-1500021
- Views 95
- Downloads 0
Role of Inflammation in the Pathogenesis of Diabetic Nephropathy.
Diabetic nephropathy is the major microvascular complication of diabetes mellitus and remains the leading cause of increased morbidity and mortality for diabetic patients. Recent evidence suggests that chronic subclinica...
Factors Responsible for Combined Glucose Intolerance Developing into Isolated Post-challenge Hyperglycemia in Subjects with Impaired Fasting Glucose
Aims/Introduction: We hypothesized that isolated post-challenge hyperglycemia (IPH) is the earliest stage of Type 2 diabetes. We conducted this study to determine factors responsible for combined glucose intolerance (CGI...
Diabetes and glycemia as predictors of peri-operative risk: a paradoxically under-characterized relationship
Diabetes and glycemia as predictors of peri-operative risk: a paradoxically under-characterized relationship
Diabetes Mellitus and male reproductive function: where we stand?
Diabetes Mellitus and male reproductive function: where we stand?
The Attitudes about Complex Therapy Scale (ACTS) in Type 2 Diabetes and Cardiovascular Disease: Development, Validity and Reliability
Background: Type 2 diabetes is associated with cardiovascular disease, and patients with both conditions are prescribed complex medication regimens. Aim: The aim was to develop a reliable and valid measure of attitudes a...