EFFECT OF AZADIRACHTA INDICA A.JUSS. AND GYNURA PROCUMBENS (MERR.) LEAF EXTRACT COMBINATION TOWARDS FREE-RADICAL SCAVENGING ACTIVITY.
Journal Title: International Journal of Advanced Research (IJAR) - Year 2019, Vol 7, Issue 9
Abstract
Introduction: The use of traditional medicine in Indonesia, especially those of herbal origin, is growing in response to the increasing price of the conventional medicine and the limited purchasing ability of the society. Extracted leaves from plants such as AzadirachtaindicaA.Juss. andGynuraprocumbens (Merr.) are examples of herbal medicine. The combination of both extract has the potential to be an antihyperglycemic agent through exploitation of its antioxidant properties. Aims & Objectives: This study focuses on testing the antioxidant activity of of a combination of ethanol extract AzadirachtaindicaA.Juss. andGynuraprocumbens (Merr.) by in vitro. Material & Methods: Antioxidant activity is tested using free radical DPPH (1,1-diphenyl-2-picrylhydrazyl) reduction method in comparison to vitamin C. The resulting antioxidant activity level of strength is determined based on IC50 values obtained. Results: antioxidant activity test showed that AzadirachtaindicaA.Juss. andGynuraprocumbens (Merr.) ethanol extract combination of 75:25 has the best IC50 value of 67.407 ?g/mL, while the 50:50 and 25:75 ethanol extract combination has IC50 value of 68.864 ?g/mL and 102.887 ?g/mL respectively. Discussion: The three combinations are weaker in comparison to the standard vitamin C antioxidant activity with IC50 value of 3.546 mg/mL. Statistical analysis using one-way ANOVA concludes significant difference in antioxidant activity of all three comparing groups. Conclusions:Gynuraprocumbens (Merr.) and Gynuraprocumbens (Merr.) extract combination of 75:25 has strong category antioxidant activity.
Authors and Affiliations
Nofran Putra Pratama , Kurnia Rahayu Purnomo Sari and Ema Mutya.
Keywords
Related Articles
- EP ID EP656810
- DOI 10.21474/IJAR01/9722
- Views 84
- Downloads 0
PREVALENCE OF ORTHOSTATIC HYPOTENSION AMONG HYPERTENSIVE PATIENTS AND HEALTHY ADULTS.
Male involvement in family planning is one of the strategies that were Orthostatic hypotension is defined as a fall in systolic blood pressure of at least 20mmHg or diastolic blood pressure of at least 10mmHg when a pers...
CHOLESTEROL MYTH FROM SCRUPULOSITY IN THE 1953 TO CERTITUDE IN 2018.
International Journal of Advanced Research (IJAR)
INVESTIGATING THE EFFECT OF NMP/PHENOL SOLVENT BLEND ON LUBRICATING OIL PROPERTIES WITHOUT/WITH USING SURFACTANT.
In this study, solvent extraction of lubricating oil to improve its viscosity index is investigated. A blend of phenol/NMP co-solvent was tested at different feed to solvent ratio 1:1, 1:1.5 and 1:2. Different percent of...
EXAMINATION OF BIOACTIVITIES ACCORDING TO THE EXTRACTION CONDITIONS OF CIRSIUM JAPONICUM VAR. USSURIENSE.
This study was carried out to obtain a basic data for application in meat products via examination of bioactive materials from Cirsium japonicum var. Ussuriense tuber. Hot water extract showed high activities against BC...
IMMUNE THROMBOCYTOPENIA. EGYPTIAN EXPERIENCE WITH STUDY OF IL-17, TGFB, CYTOKINES IN CHRONIC AND PERSISTENT IMMUNE THROMBOCYTOPENIA PATIENTS.
Background: Autoimmune diseases are characterized by various factors that contribute to a breakdown in self tolerance. In this study we review the demographic features of 150 immune thrombocytopenic Egyptian patients and...