Effect of bee Propolis Supplementation on Insulin Resistance Indices in Patients with Type 2 Diabetes: a Randomized Double-Blind Clinical Trial
Journal Title: The Journal of Tolooebehdasht - Year 2017, Vol 16, Issue 1
Abstract
Introduction: Diabetes mellitus is a common endocrine disease . The number of people with diabetes over the last twenty years has doubled . Asia as a result of rapid economic growth, as the center of the epidemic in the world. Iran is among the countries with a high prevalence of diabetes mellitus. Use of medicinal plants as adjunctive therapy along with medication always been original. In recent years the tendency of patients to alternative therapies and traditional medicine has increased. Methods: Among patients referred to clinics of University of Medical Sciences, Yazd, Iran, 67 people were selected and randomly divided into two groups,intervention or placebo. Patients in the intervention group received 3 tablets of 300 mg bee propolis and in the control group received placebo. The study lasted 12 weeks. Serum insulin and insulin resistance index were evaluated at the beginning and end of the study. Results: 57 patients completed the study. The average demographic characteristics , anthropometric indices , serum insulin and insulin resistance index at the beginning and end of the study between the two groups showed no significant difference. Conclusion: In this study, supplementation with bee propolis for 12 weeks, on the serum insulin and indices of insulin resistance in patients with type II diabetes is not effective. Further studies are needed to make a final decision.
Authors and Affiliations
Nazli Samadi, Hassan Mozaffari-Khosravi, Masood Rahmanian, Mohsen Asgari Shahi
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