Effect of calcium hydroxide and mineral trioxide aggregate on human PDL fibroblast: an in vitro study
Journal Title: International Journal of Allied Medical Sciences and Clinical Research - Year 2018, Vol 6, Issue 1
Abstract
Background and Aim The aim of this in vitro study was to investigate the effect of Calcium hydroxide and MTA (Mineral Trioxide Aggregate) on human periodontal ligament fibroblast (PDL). Method The cements were divided into three groups Group 1: Calcium hydroxide, Group 2: MTA and Group 3: Calcium hydroxide + MTA. PDL fibroblasts were cultured in above groups. The proliferations of cells were recorded under microscope. Results Group 2 showed no lysis of PDL fibroblasts, whereas Group 1 and Group 3 were found slight toxic in nature as they inhibited the PDL cell proliferation. Conclusion MTA provided a more favourable environment for PDL fibroblasts adhesion and proliferation.
Authors and Affiliations
Pallavi Giridhar Sonawane
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