Effect of Clonidine Addition To Hyperbaric 0.5% Bupivacaine For Spinal Anaesthesia In Lower Limb Surgery [A Comparative Study]
Journal Title: National Journal of Integrated Research in Medicine - Year 2012, Vol 3, Issue 1
Abstract
Background: The use of subarachnoid block has become an established and reliable method of providing anaesthesia for lower abdominal and lower limb surgery. Regional anaesthesia is generally well tolerated by all patients, producing less postoperative confusion and delirium than general anesthesia. It is also associated with lesser incidence of post-operative thromboembolism. However subarachnoid block has got its own inherent complications, especially related to cardiovascular stability.Aim: to compare the haemodynamic ,sensory and motor effects of a low dose bupivacaine – clonidine spinal anesthesia versus conventional dose of bupivacaine in patients undergoing lower limb surgery.Method: Prospective, randomized double blind study was undertaken in 60 selected patients posted for lower limb surgeries. Data were collected for duration and onset of motor and sensory effects, haemodynamic changes and side effects of study drugs and they were statistically analyzed.Results: We found in our study that time of onset of adequate level of sensory block (T10) was significantly longer for group B which contains 30μ gm of clonidine (126±14) than group A (95±10). The total duration of sensory block for Group A was 227.6±9.8 mins while Group B had 351.9± 17.5 mins and motor block for group A was 162.5±7.51 mins while in group B had 274.8±14.4 mins. Conclusion: Clonidine when combined with low dose bupivacaine has prolonged the duration of motor and sensory blockage and incidence of intra operative pain with maintaining haemodynamic stability. [ Chand K et al NJIRM 2012; 3(1) : 113-119].
Authors and Affiliations
Dr. Ramila H. Jamliya, Dr. Reema Vansola, Dr. B. J. Shah, r. Dharmesh L Chauhan
Keywords
Related Articles
- EP ID EP40195
- DOI -
- Views 373
- Downloads 0
Diaphysial Nutrient Foramina In Long Bones And Miniature Long Bones
Background: Nutient foramen is an opening into the bone shaft which gives passage to the blood vessels of the medullary cavity of a bone. The knowledge of nutrient foramen is important in surgical procedures like bone...
A Comparative Study of Serum Lipid Profile between Premenopausal And Postmenopausal Women
Background & objectives: The effect of the hormonal changes associated with menopause on the serum lipid levels may play an important role in most cardiac related disorders associated with menopause. So the present stu...
Evaluation of frequency of abnormal Urine R.E tests in Pathology Laboratory
Objective To evaluate the frequency of abnormal urine routine examination (RE) in order to justify the clinician's frequent requests and use of test either as diagnostic aid to confirm provisional clinical diagnosis or...
Effect of Clonidine Addition To Hyperbaric 0.5% Bupivacaine For Spinal Anaesthesia In Lower Limb Surgery [A Comparative Study]
Background: The use of subarachnoid block has become an established and reliable method of providing anaesthesia for lower abdominal and lower limb surgery. Regional anaesthesia is generally well tolerated by all patie...
Syndrome of Malnutrition-Inflammation Complex in Chronic Alcoholics
Several studies have reported elevated serum ferritin levels in patients of chronic alcohol abuse. We hypothesized that serum ferritin may be acting as a marker of acute phase reactant, reflecting the inflammatory statu...