Effect of Coagulation Profile in Third Trimester of Pregnancy

Journal Title: Journal of Medical Science And clinical Research - Year 2014, Vol 2, Issue 10

Abstract

Normal pregnancy associated with many changes in coagulation profile. These changes are important for intrapartum blood loss and also for thromboembolism during pregnancy and labour. The present study aimed at to find out the quantitative change in coagulation profile in early and later part of third trimester. This study was carried out in the Department of physiology, AMC, Dibrugarh, Assam. 50 cases of pregnant women in third trimester are enrolled for the study. Among which 29 cases are in 29th to 34th wks and 21 cases are within 35th to 39th wks of gestation. For control 50 ages matched healthy female of child bearing age group are taken. Platelet count , Bleeding time and coagulation time were done in each control and cases. The mean platelet count in pregnancy at 29th to 34th wks was more than that of non pregnant but the value was less in pregnancy at 35th to 39th wks. Similarly mean bleeding time and coagulation time was also increases in third trimester than the non pregnant. But both the values are decreases in 35th to 39th wks than the 29th to 34th wks. Platelet count was progressively decreased in later part of pregnancy women compared to non pregnant women. It is partly due to hemodilution and partly due to increased platelet activation and accelerated clearance (Shehlata et al., 1999 and McCrae, 2010).To conclude thromboembolism and bleeding disorder are two major complications of pregnancy. So to prevent the complication proper study of coagulation profile is necessary

Authors and Affiliations

Dr Tazkira Begum

Keywords

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  • EP ID EP207879
  • DOI -
  • Views 77
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How To Cite

Dr Tazkira Begum (2014). Effect of Coagulation Profile in Third Trimester of Pregnancy. Journal of Medical Science And clinical Research, 2(10), 2559-2566. https://europub.co.uk/articles/-A-207879