Effect of Dexmedetomidine as an adjuvant to General Anesthesia during abdominal surgeries
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 3
Abstract
Abstract: Dexmedetomidine is aα2 -adrenoreceptor agonist with sedative, analgesic and anxiolytic properties it is known to be used as General Anesthetic adjuvant. It has useful action like minimal respiratory depression with Cardioprotection, Neuroprotection and Renoprotection with added advantages like anesthetic and analgesic sparing actions. In the present we tried to evaluate the effect of dexmedetomidine as anesthetic adjuvant on variables and postoperative pain scores and need for rescue analgesics and anti-emetics and resumption of bowel function. The study was performed in CAIMS Karimnagar. 60 patients divided into three groups of 20 each were randomly selected and allotted. The patients were undergoing various abdominal surgical procedures like Laparoscopic Cholecystectomy, Hysterectomy and Appendectomy. The first group (Group I) was the control group they received IV saline 10ml, the second group (Group II) was the [Dex 0.5] group they received Dexmedetomidine 0.5 µg/Kg/hr IV and third group (Group III) [Dex 1.0] received Dexmedetomidine 1 µg/Kg/hr IV. Anesthesia was maintained with N2O to O2 mixture of 60:40. MAP values were maintained within 25% of the baseline values. Recovery times from tracheal extubation, modified Alderete score, VAS scores, tolerating liquids, and passage of flatus were noted. Mean duration of surgery was 156 ± 25, 140 ± 30 and 126 ± 45 in group I, Group II and Group III respectively. Time to suction catheter response was 7.31 ± 1.87, 8.10 ± 2.29 and 8.56 ± 3.67 mins in the Group I, II, III and Modified Aldrete score of > 8 was achieved earliest by Group III with mean value of 5.9 ± 3.5 which was statistically significant. The VAS scores (0-10) were 6.8 ± 1.5, 5.5 ± 1.0 and 5.2 ± 1.5 were recorded in the Group I, II and III. Dexmedetomidine is a useful adjunct to anesthesia because of its beneficial effects on postoperative analgesia and recovery. Dexmedetomidine was found to be useful in abdominal laparoscopic procedures where the duration of surgery is lesser. It also reduces the operative sevoflurane requirements without any adverse effects. Keywords:Dexmedetomidine, Adjuvant, Abdominal Surgeries
Authors and Affiliations
Bhimireddy Venkata reddy, Jaya Babu Nagula
Keywords
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