Effect of Dexmedetomidine as an Adjuvant to Lignocaine and Bupivacaine Used in Tranversus Abdominis Plane (TAP) Block for Postoperative Pain Relief
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2018, Vol 6, Issue 2
Abstract
Abstract: Our aimed to evaluate the effect of dexmedetomidine as an adjuvant to lignocaine and bupivacaine used in tranversus abdominis plane (TAP) block for postoperative pain relief. Randomized study of 50 patients scheduled for abdominal hysterectomy was divided into two equal groups in a randomized double-blinded in this study. Group A (Control) patients (n = 25) received TAP block with 10 ml of 0.25% bupivacaine, with 10 ml of 2% lignocaine bilaterally while Group B (Dexmedetomidine) patient (n = 25) received 0.5 mcg/kg (2 ml) of dexmedetomidine, with 10 ml of 2% lignocaine and 10 ml of 0.25% bupivacaine bilaterally. Time for first analgesic administration and side-effects were recorded. There is a statistically significant difference in the time for first analgesic and pain score for 24 hours between the two groups (p value< 0.05). The time for the first demand of rescue analgesia was earlier in group A, 246.60 ± 28.22 min as compared to group B, i.e. 613.90 ± 67.72 min. (p value < 0.05). The average VAS score for the 24 hours was lower in group A 4.98 ± 0.77 than in group B, i.e5.18 ± 1.02. (p <0.05). The addition of dexmedetomidine to local anesthetic agent in TAP block helps achieve better analgesia and decreases the total dose of analgesics required post-operatively without any major side-effects.
Authors and Affiliations
Dr. K. K. Khan, Dr. Shashank Dhaketa, Dr. Sagar Rakesh Tyagi, Dr. Shiva Dwivedi, Dr. Barkha Dodani
Keywords
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