Effect of dexmedetomidine on consumption of anesthetic agents, duration of surgery, time to extubationand post-operative emergence during endoscopic nasal surgeries: a pilot study
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 6
Abstract
Abstract: Our aim was to study the effects of dexmedetomidine on anesthetic consumption, duration of surgery, time to extubation and post-operative emergence when used as an adjunct to general anesthesia in endoscopic nasal surgeries. Fifty two patients scheduled for elective nasal surgery (Functional Endoscopic Sinus Surgery and Functional Endoscopic Nasal surgery) were randomized into two groups.Dexmedetomidine - group (D) and placebo or control - group (C).Dexmedetomidine was administered to the D group at a bolus dose of 0.5 ug/kg via an intravenous infusion pump over 10 min. Intraoperative maintenance was supplied by a continuous infusion of 0.2 ug/kg/hr. Infusion of Dexmedetomidine was stopped when the major surgical intervention was over.Group C was given equal amounts of normal saline, instead of Dexmedetomidine.The intraoperative hemodynamics during the surgery were recorded on a proforma. The duration of surgery, time to extubation and amount of anesthetic agents consumed in both the groups were noted. We found that there was a statistically significant difference in anesthetic consumption between both groups. The time to extubation was more in group C(p value < 0.05) .Awakening scores were better in group D(p value < 0.05).No significant difference in the duration of surgery was found.Our conclusion was that Dexmedetomidine reduces anesthetic agent consumption significantly when used as an adjunct in endoscopic nasal surgeries, thereby leading to shorter extubation times and better awakening scores. Keywords:Dexmedetomidine, endoscopicsurgeries,propofol,sevoflurane,controlled hypotension,awakening score.
Authors and Affiliations
Dr. Harpreet Kaur, Dr. Rajeev Lochan Tiwari, Dr. Jyotsna Bhargava, Dr. Neeraj Kasliwal
Keywords
Related Articles
- EP ID EP371564
- DOI -
- Views 78
- Downloads 0
Impact of Electronic Media on Sleep
Abstract: With technological advances there is increase in usage of electronic gadgets like computer, cell phone, MP3 player, tablet, game console, television, TV-games and computer games. With electronic media and soci...
The use of three dimensional hysterosonography in recurrent implantation failure prior to in vitro fertilization cycles
Abstract: Recurrent implantation failure can be due to endometrial cavity abnormalities or abnormal endometrial thickness, hysteroscopy and hysterosonography can be used to evaluate the presence of endometrial polyps, su...
Glutathione Peroxidase and Its Correlation with the Marker of Lipid Peroxidation in Essential Hypertension Patients
The present study was carried out to estimate the erythrocyte glutathione peroxidase activity, an antioxidant enzyme and malondialdehyde (marker of lipid peroxidation) in Hypertensive subjects of different grades as per...
Students’ perception of their Educational Environment in a Medical College in Odisha, India
Abstract:Learning environment in any medical school is found to be important in determining students' academic success. There is a need to evaluate perceptions of the educational environment of training institutions for...
Study of Prevalence and Risk Factors of Non-Fatal Road Traffic Accidents in Ruralpopulation of District Dehradun
Abstract: To study the prevalence and various environmental risk factors related to Road Traffic Accidental injuries in rural population of district Dehradun.A cross-sectional descriptive study was conducted in rural are...