Effect of dexmedetomidine on consumption of anesthetic agents, duration of surgery, time to extubationand post-operative emergence during endoscopic nasal surgeries: a pilot study
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 6
Abstract
Abstract: Our aim was to study the effects of dexmedetomidine on anesthetic consumption, duration of surgery, time to extubation and post-operative emergence when used as an adjunct to general anesthesia in endoscopic nasal surgeries. Fifty two patients scheduled for elective nasal surgery (Functional Endoscopic Sinus Surgery and Functional Endoscopic Nasal surgery) were randomized into two groups.Dexmedetomidine - group (D) and placebo or control - group (C).Dexmedetomidine was administered to the D group at a bolus dose of 0.5 ug/kg via an intravenous infusion pump over 10 min. Intraoperative maintenance was supplied by a continuous infusion of 0.2 ug/kg/hr. Infusion of Dexmedetomidine was stopped when the major surgical intervention was over.Group C was given equal amounts of normal saline, instead of Dexmedetomidine.The intraoperative hemodynamics during the surgery were recorded on a proforma. The duration of surgery, time to extubation and amount of anesthetic agents consumed in both the groups were noted. We found that there was a statistically significant difference in anesthetic consumption between both groups. The time to extubation was more in group C(p value < 0.05) .Awakening scores were better in group D(p value < 0.05).No significant difference in the duration of surgery was found.Our conclusion was that Dexmedetomidine reduces anesthetic agent consumption significantly when used as an adjunct in endoscopic nasal surgeries, thereby leading to shorter extubation times and better awakening scores. Keywords:Dexmedetomidine, endoscopicsurgeries,propofol,sevoflurane,controlled hypotension,awakening score.
Authors and Affiliations
Dr. Harpreet Kaur, Dr. Rajeev Lochan Tiwari, Dr. Jyotsna Bhargava, Dr. Neeraj Kasliwal
Keywords
Related Articles
- EP ID EP371564
- DOI -
- Views 65
- Downloads 0
Laparoscopic Evaluation of Adnexal Masses in Reproductive Age Group
Adnexal masses are one of the most common pathologies among women of all age groups. The aim of the present study was to study laparoscopic diagnosis of adnexal masses in the reproductive age group and to study the spect...
Nalbuphine as an Alternate Analgesic to Morphine in Total Abdominal Hysterectomy: A Prospective, Randomized, Comparative, Double-Blind Study
: Pain is one of the most distressing post-operative consequences of surgeries. Opioids have been the mainstay in providing pain relief. Morphine is the considered to be the “gold standard” amongst opioids as an analgesi...
Study of breastfeeding practices amongst PNC mothers in urban slum areas in Solapur city, Maharashtra
Since 1993, WHO’s effort to improve infant and young child nutrition have focused on promoting breastfeeding. It is estimated that suboptimal breastfeeding especially non-exclusive in first six months of life results in...
Tubularised Incised Plate Urethroplasty with Spongioplasty and Tunica Vaginalis Flap in Hypospadias Repair- A Case Series of 30 Cases
Abstract: The objective of the study was to evaluate the cosmetic and functional results of tabularised incised plate (tip) urethroplasty with spongioplasty and tunica vaginalis flap in hypospadias repair. From February...
Blood Component Therapy in the ICU for the Paediatric Patient
Abstract: Blood and its components have been as important as drugs in the medical armamentarium. Whole blood on processing furnishes packed RBCs, platelets, plasma, cryoprecipitate, immunoglobulins, albumin, and specific...